Definition of Naturally Processed Peptides Reveals Convergent Presentation of Autoantigenic Topoisomerase I Epitopes in Scleroderma. [PDF]
, 2020 ObjectiveAutoimmune responses to DNA topoisomerase I (topo I) are found in a subset of scleroderma patients who are at high risk for interstitial lung disease (ILD) and mortality.
Boin, Francesco +9 more
core +1 more source
LDPC codes associated with linear representations of geometries [PDF]
, 2010 We look at low density parity check codes over a finite field K associated with finite geometries T*(2) (K), where K is any subset of PG(2, q), with q = p(h), p not equal char K. This includes the geometry LU(3, q)(D), the generalized quadrangle T*(2)(K)
Vandendriessche, Peter
core +1 more source
The Finite Field Kakeya Problem [PDF]
, 2008 A Besicovitch set in AG(n,q) is a set of points containing a line in every direction. The Kakeya problem is to determine the minimal size of such a set.
A. Bichara +8 more
core +2 more sources
Co-lethality studied as an asset against viral drug escape: the HIV protease case [PDF]
, 2010 International audienceBackground: Co-lethality, or synthetic lethality is the documented genetic situation where two, separately non-lethal mutations, become lethal when combined in one genome.
Anne Vanet +4 more
core +5 more sources
Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection [PDF]
, 2018 Significance The emergence of multidrug-resistant bacteria, including uropathogenic Escherichia coli (UPEC), makes the development of targeted antivirulence therapeutics a critical focus of research.
Chugani, Ryan +8 more
core +2 more sources
A handheld diagnostic system for 6LoWPAN networks [PDF]
, 2017 The successful deployment of low-power wireless sensor networks (WSNs) in real application environments is a much broader exercise than just the simple instrumentation of the intended monitoring site. Many problems, from node malfunctions to connectivity
core +2 more sources
Projective simulation for artificial intelligence [PDF]
, 2012 We propose a model of a learning agent whose interaction with the environment is governed by a simulation-based projection, which allows the agent to project itself into future situations before it takes real action.
Andy Clark +22 more
core +3 more sources
Small, Low-energy, Dispersive Solar Energetic Particle Events Observed by Parker Solar Probe [PDF]
, 2020 The Energetic Particle Instrument–Low Energy (EPI-Lo) experiment has detected several weak, low-energy (~30–300 keV nucleon⁻¹) solar energetic particle (SEP) events during its first two closest approaches to the Sun, providing a unique opportunity to ...
Allen, R. C. +26 more
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Synthetic biology—putting engineering into biology [PDF]
, 2006 Synthetic biology is interpreted as the engineering-driven building of increasingly complex biological entities for novel applications. Encouraged by progress in the design of artificial gene networks, de novo DNA synthesis and protein engineering, we ...
Heinemann, Matthias,, Panke, Sven,
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RNA from a simple-tandem repeat is required for sperm maturation and male fertility in Drosophila melanogaster. [PDF]
, 2019 Tandemly-repeated DNAs, or satellites, are enriched in heterochromatic regions of eukaryotic genomes and contribute to nuclear structure and function. Some satellites are transcribed, but we lack direct evidence that specific satellite RNAs are required ...
Allshire +44 more
core +2 more sources