Results 131 to 140 of about 465,440 (342)

Beam Switching in mmWave 5G: Evaluation in a Realistic Industrial Scenario

open access: yesIEEE Access
Fifth Generation (5G) Millimeter cellular networks are particularly interesting within the Industry 4.0 paradigm. mmWaves provide flexibility to the industrial use case, as well as enable specific application requirements, e.g.
Antonio Tarrias   +6 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Urban flood drifters (UFD): Identification, classification and characterisation

open access: yesJournal of Flood Risk Management
Extreme floods threaten lives, assets and ecosystems, with the largest impacts occurring in urbanised areas. However, flood mitigation schemes generally neglect the fact that urban floods carry a considerable amount of solid load.
Arnau Bayón   +2 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Variations in the technical performance of elite female volleyball: evidence from a new round model

open access: yesScientific Reports
Volleyball athletes’ performance can vary between different micro-phases of the competition. This study aimed to investigate distinctions in volleyball athletes’ technical performance among rounds employing a novel volleyball round model.
Yuwei Shen, Muzi Li, Qing Yang
doaj   +1 more source

Shared genetic risk and causal associations between Post-traumatic stress disorder and migraine with antithrombotic agents and other medications

open access: yesNeurobiology of Stress
Post-traumatic stress disorder (PTSD) is a psychiatric disorder that frequently co-occurs with pain disorders including migraine. There are proposed biological, genetic and environmental factors associated with both PTSD and migraine suggesting shared ...
Charlotte K. Bainomugisa   +5 more
doaj   +1 more source

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