Results 131 to 140 of about 174,644 (291)

Statistics in piling block games

open access: yesStatistics in piling block games
Using a computer, we have computed exactly the probability to describe the statistical properties of a pile of blocks in the case that when a child puts a block on the topmost block its center of mass is shifted to the right or left by the unit length with equal probability. The block length is restricted into positive integers.
openaire  

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Closed-form Output Statistics of MIMO Block-Fading Channels [PDF]

open access: green, 2014
G. Alfano   +3 more
openalex   +1 more source

Statistical thermodynamics of block copolymer adsorption

open access: yes
The aim of this study was to develop a statistical thermodynamic theory for the adsorption of linear flexible block copolymers from a multicomponent solution. This has been accomplished by a more general derivation of the self-consistent field theory of Scheutjens and Fleer for adsorption of homopolymer from a binary mixture, introducing local segment ...
openaire   +2 more sources

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

open access: yesFEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani   +7 more
wiley   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

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