Results 131 to 140 of about 440,099 (344)
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
Beam Switching in mmWave 5G: Evaluation in a Realistic Industrial Scenario
IEEE AccessFifth Generation (5G) Millimeter cellular networks are particularly interesting within the Industry 4.0 paradigm. mmWaves provide flexibility to the industrial use case, as well as enable specific application requirements, e.g.
Antonio Tarrias +6 more
doaj +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Timber resource statistics for the Willow block, Susitna River Basin multiresource inventory unit, Alaska, 1978. [PDF]
, 1984 Theodore S. Setzer +2 more
openalex +1 more source
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
SensorsInfrared line-scanning images have high redundancy and large file sizes. In JPEG2000 compression, the MQ arithmetic encoder’s complexity slows down processing. Huffman coding can achieve O(1) complexity based on a code table, but its integer-bit encoding
Yaohua Zhu +5 more
doaj +1 more source
Earthquake statistics in a Block Slider Model and a fully dynamic Fault Model [PDF]
, 2004 Dion Weatherley, Steffen Abe
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Statistical inference for block sparsity of complex signals
, 2019 Block sparsity is an important parameter in many algorithms to successfully recover block sparse signals under the framework of compressive sensing. However, it is often unknown and needs to be estimated. Recently there emerges a few research work about how to estimate block sparsity of real-valued signals, while there is, to the best of our knowledge,
Wang, Jianfeng, Zhou, Zhiyong, Yu, Jun
openaire +2 more sources
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source