Results 151 to 160 of about 451,265 (323)

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

FEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr, Michael Fauler, Thomas Zimmer, Bettina Jungwirth, Hubert Schrezenmeier, David Alexander Christian Messerer   +5 more
wiley   +1 more source

Detection of Bundle Branch Block using Higher Order Statistics and Temporal Features

, 2021
Yasin Kaya
openalex   +1 more source

High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer

FEBS Open Bio, EarlyView.
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson, Lisa Lif, Husam Oda, Alexandra Lorenzzi de Melo, David Lindquist, Håkan Hedman   +5 more
wiley   +1 more source

Dark versus blocking states in electronic transport: a Lee-Yang zero analysis of full counting statistics [PDF]

Johann Philipp Zöllner, Philipp Stegmann, Jürgen König, Eric Kleinherbers   +3 more
openalex   +1 more source

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

FEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source

Block Estimation Technique in Spatial Statistics With Application

, 2023
Jaufar Mousa Mohammed AL-bayati
openalex   +2 more sources

Sharp finite statistics for minimum data block sizes in quantum key distribution [PDF]

Vaisakh Mannalath, Víctor Zapatero, Marcos Curty   +2 more
openalex   +1 more source

Does higher sampling rate (multiband + SENSE) improve group statistics - An example from social neuroscience block design at 3T

, 2020
Ritu Bhandari, Evgeniya Kirilina, Matthan W.A. Caan, Judith Suttrup, Teresa De Sanctis, L. De Angelis, Christian Keysers, Valeria Gazzola   +7 more
openalex   +1 more source

NOMA Joint Decoding based on Soft-Output Ordered-Statistics Decoder for Short Block Codes [PDF]

, 2022
Chentao Yue, Alva Kosasih, Mahyar Shirvanimoghaddam, Giyoon Park, Ok-Sun Park, Wibowo Hardjawana, Branka Vucetic, Yonghui Li   +7 more
openalex   +1 more source