A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
How thoughtful experimental design can empower biologists in the omics era. [PDF]
Wagner MR, Kleiner M.
europepmc +1 more source
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Novel no-reference image blur metric based on block-based discrete cosine transform statistics [PDF]
Yu Han
openalex +1 more source
Forgery localization in images based on joint statistics of image blocks with neighbouring blocks
Divya Singhal, Abhinav Gupta
openalex +1 more source
Towards accurate penetration depth estimation in near-infrared spectroscopy: a quantitative analysis of source-detector distance dependence in porcine kidney models. [PDF]
Khurana AS +3 more
europepmc +1 more source
Decoding of linear block codes based on ordered statistics
M.P.C. Fossorier
openalex +1 more source
RTP Control Protocol (RTCP) Extended Report (XR) Block for MPEG-2 Transport Stream (TS) Program Specific Information (PSI) Independent Decodability Statistics Metrics Reporting [PDF]
R. Huang, Aiqing Wu, H. Asaeda, G. Zorn
openalex +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Polyserine domains are toxic and exacerbate tau pathology in mice. [PDF]
Van Alstyne M +3 more
europepmc +1 more source

