Results 211 to 220 of about 465,440 (342)

A novel perspective on blocking statistics

, 2021
openaire   +1 more source

STATISTICAL ESTIMATION AND BLOCKING COALITIONS，1

STATISTICAL ESTIMATION AND BLOCKING COALITIONS，1
経営と経済, 62(3), pp.99-103 ...
openaire  

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Impact of Electronic Prescribing on Parkinson's Disease Medication Management: A Retrospective Before-and-After Audit at a UK Teaching Hospital. [PDF]

Cureus
Omer YZ, Chakraborty M, Phillips K, Ponniah G, Strens L.   +4 more
europepmc   +1 more source

Comparisons of Experimentally and Numerically Determined Statistics for Predicting Low-Occurrence Wind Speeds Around a 1:1:2 Block Model

Tingzhou Tong, Yezhan Li, Wei Wang, MF Faizal, Tsubasa Okaze, Naoki Ikegaya   +5 more
openalex   +1 more source

Summary statistics from "Impact of medication on blood transcriptome reveals off-target regulations of beta-blockers"

, 2022
Michael Rode, Kolja Nenoff, Kerstin Wirkner, Katrin Horn, Andreij Teren, Ralf Regenthal, Markus Loeffler, Joachim Thiery, Achim Aigner, Janne Pott, Holger Kirsten, Markus Scholz   +11 more
openalex   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Crystal structure and nanobodies against domain 3 of the malaria parasite fusogen Plasmodium falciparum HAP2. [PDF]

Biochem J
Lyons FMT, Chmielewski J, Chan LJ, Gabriela M, Chan RWB, Adair A, Tong J, Pymm P, Zeglinski K, Gouil Q, Tham WH, Dietrich MH.   +11 more
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Surface hydrophobicity and rigidity determines protein corona on orally delivered nanoparticles treating colitis. [PDF]

Nat Commun
Wu J, Ni M, Xing L, Wang Y, Liu X, Zheng Y, Li L, Huang Y.   +7 more
europepmc   +1 more source