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Strategies for delivering therapeutics across the blood–brain barrier
Nature reviews. Drug discovery, 2021G. Terstappen +3 more
semanticscholar +1 more source
Journal of neuroradiology = Journal de neuroradiologie, 1990
The blood-brain barrier (BBB) is present on three sites: the brain vessels, the choroid plexus and the arachnoid membrane. It is made of non-fenestrated endothelial or epithelial cells interconnected by tight junctions. Biochemically, the BBB is formed by bimolecular layers of phospholipids into which globular proteins are inserted.
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The blood-brain barrier (BBB) is present on three sites: the brain vessels, the choroid plexus and the arachnoid membrane. It is made of non-fenestrated endothelial or epithelial cells interconnected by tight junctions. Biochemically, the BBB is formed by bimolecular layers of phospholipids into which globular proteins are inserted.
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Astrocyte–endothelial interactions at the blood–brain barrier
Nature Reviews Neuroscience, 2006N. Abbott, L. Rönnbäck, E. Hansson
semanticscholar +1 more source
1971
The concept of a barrier between blood, on the one hand, and the brain on the other derives from the classical studies of Ehrlich and of Goldmann on vital staining; it was noted that a large variety of acid dyes, of which trypan blue was one, would pass out of the blood into the tissues of the body making them voloured; the brain and spinal cord stood ...
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The concept of a barrier between blood, on the one hand, and the brain on the other derives from the classical studies of Ehrlich and of Goldmann on vital staining; it was noted that a large variety of acid dyes, of which trypan blue was one, would pass out of the blood into the tissues of the body making them voloured; the brain and spinal cord stood ...
openaire +2 more sources
2019
Blood–brain barrier characteristics are analyzed, which must be considered to be much more than a connective supporting tissue between the neurons and the capillary endothelium.
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Blood–brain barrier characteristics are analyzed, which must be considered to be much more than a connective supporting tissue between the neurons and the capillary endothelium.
openaire +2 more sources
The Blood-Brain Barrier/Neurovascular Unit in Health and Disease
Pharmacological Reviews, 2005B. Hawkins, T. Davis
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The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
Neuron, 2008B. Zlokovic
semanticscholar +1 more source
, 2014