Results 91 to 100 of about 86,370 (197)
Therapeutic Effects of Anthocyanins for Vision and Eye Health
Molecules, 2019 Anthocyanin (AC) is widely used as supplement of eye health in Europe and in East Asia. In this review, I describe AC effects to clarify the mechanism is important in order to understand the effects of AC on vision health.
Yuri Nomi +2 more
doaj +1 more source
Breakdown of the Blood–Retinal Barrier
, 2010 Macular edema that results from blood–retinal barrier (BRB) breakdown is a cause of significant visual loss associated with a variety of ocular disorders. BRB breakdown is a complex process that is regulated by multiple factors and involves different mechanisms.
openaire +1 more source
BiologyThe retina is highly sensitive to oxygen and blood supply, and hypoxia plays a key role in retinal diseases such as diabetic retinopathy (DR) and age-related macular degeneration (AMD).
Alaa M. Mansour +3 more
doaj +1 more source
New and emerging technologies for the treatment of inherited retinal diseases: a horizon scanning review. [PDF]
, 2015 The horizon scanning review aimed to identify new and emerging technologies in development that have the potential to slow or stop disease progression and/or reverse sight loss in people with inherited retinal diseases (IRDs).
Michaelides, M +4 more
core
Journal of Ophthalmology, 2017 Ocriplasmin (Jetrea®) is a recombinant protease used to treat vitreomacular traction. To gain insight into vitreoretinal observations reported after ocriplasmin treatment, we have developed an in vivo porcine ocriplasmin-induced posterior vitreous ...
Bart Jonckx +5 more
doaj +1 more source
The Blood–Retinal Barrier in Retinal Disease
European Ophthalmic Review, 2009 The blood–ocular barrier system is formed by two main barriers: the blood–aqueous barrier and the blood–retinal barrier (BRB). The BRB is particularly tight and restrictive and is a physiological barrier that regulates ion, protein and water flux into and out of the retina.
openaire +1 more source
Preclinical translation of exosomes derived from mesenchymal stem/stromal cells. [PDF]
, 2020 Exosomes are nanovesicles secreted by virtually all cells. Exosomes mediate the horizontal transfer of various macromolecules previously believed to be cell-autonomous in nature, including nonsecretory proteins, various classes of RNA, metabolites, and ...
Anderson, Johnathon D +3 more
core
A Patient Centered Intervention to Promote Primary Care Based Screening for Diabetic Retinopathy [PDF]
, 2018 Diabetic Retinopathy is the leading cause of blindness in patient\u27s age 25-74 in the world. Onset of disease is insidious and early intervention is the only way to reduce morbidity.
Earle, William B
core +1 more source
The blood-retinal barrier in chloroquine retinopathy.
Investigative ophthalmology & visual science, 1989 Chloroquine retinopathy can result in devastating loss of vision. To date, there are no effective and reliable methods of detecting the toxicity at an early stage when retinopathy may be reversible. Chloroquine is deposited in the retinal pigment epithelium, which forms part of the blood-retinal barrier (BRB). By vitreous fluorophotometry we have shown
M F, Raines, S K, Bhargava, E S, Rosen
openaire +1 more source
Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells. [PDF]
, 2017 PurposeThe RPE cell line ARPE-19 provides a dependable and widely used alternative to native RPE. However, replication of the native RPE phenotype becomes more difficult because these cells lose their specialized phenotype after multiple passages ...
Duncan, Todd +8 more
core +2 more sources