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Strategies for delivering therapeutics across the blood–brain barrier
Nature Reviews Drug Discovery, 2021Georg C Terstappen, Wandong Zhang
exaly
Diseases Affecting the Inner Blood-Retinal Barrier
1980The inner blood-retinal barrier (I-BRB) is affected by a surprising array of ocular diseases, often with deterioration of vision. These retinal vasculopathies can be classified1’2 within the following eight categories: stretching of the vascular wall; hypoxia; metabolic (chemical, physiologic, and pharmacologic) alterations; inflammatory processes ...
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Estimation of permeability in blood-retinal barrier.
[Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1990Permeability of the blood-retinal barrier (BRB) can be determined by vitreous fluorophotometry and computer analysis. In this study, we characterize our eye model and apply it to normal human subjects. In this investigation of BRB permeability, we employed four parameters for the eye model: the inward permeability (Pin) and outward permeability (Pout ...
M, Kojima +3 more
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Fluorescein Angiography and the Blood-Retinal Barrier
1980Fluorescein is a real “providence” for the study of barriers. And reciprocally, the existence of barriers is a real “providence” for the analysis of angiograms.
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The blood–tumour barrier in cancer biology and therapy
Nature Reviews Clinical Oncology, 2021Patricia S Steeg
exaly
Blood-retinal barriers in health and disease.
Transactions of the ophthalmological societies of the United Kingdom, 1982The blood-retinal barrier (BRB) is located at two levels, forming an outer barrier in the retinal pigment epithelium and an inner barrier in the endothelial membrane of the retinal vessels. Both these membranes have tight junctions of the 'non-leaky' type and cellular transport processes predominate.
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