Results 11 to 20 of about 86,370 (197)
The inner blood-retinal barrier: Cellular basis and development
Vision Research, 2017 The blood-retinal barrier (BRB) regulates transport across retinal capillaries maintaining proper neural homeostasis and protecting the neural tissue from potential blood borne toxicity. Loss of the BRB contributes to the pathophysiology of a number of blinding retinal diseases including diabetic retinopathy. In this review, we address the basis of the
Mónica, Díaz-Coránguez +2 more
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Pathological high intraocular pressure induces glial cell reactive proliferation contributing to neuroinflammation of the blood-retinal barrier via the NOX2/ET-1 axis-controlled ERK1/2 pathway [PDF]
Journal of NeuroinflammationBackground NADPH oxidase (NOX), a primary source of endothelial reactive oxygen species (ROS), is considered a key event in disrupting the integrity of the blood-retinal barrier.
Xin Shi +10 more
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Involvement of moesin phosphorylation in ischemia/reperfusion induced inner blood-retinal barrier dysfunction [PDF]
International Journal of Ophthalmology, 2020 AIM: To investigate the role of moesin and its underlying signal transduction in retinal vascular damage induced by retinal ischemia-reperfusion (RIR) insult.
Jing Xu +6 more
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Disruption of outer blood-retinal barrier by Toxoplasma gondii-infected monocytes is mediated by paracrinely activated FAK signaling. [PDF]
PLoS ONE, 2017 Ocular toxoplasmosis is mediated by monocytes infected with Toxoplasma gondii that are disseminated to target organs. Although infected monocytes can easily access to outer blood-retinal barrier due to leaky choroidal vasculatures, not much is known ...
Hyun Beom Song +5 more
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Pathogenesis of diabetic macular edema: role of the glial factor (literature review and own data)
Mìžnarodnij Endokrinologìčnij Žurnal, 2023 The review presents modern data on the pathogenesis of diabetic macular edema. Today, a new understanding of the pathophysiology of diabetic retinal lesions includes structural dysfunction of the neurovascular unit (NVU) of the retina.
M.L. Kyryliuk, S.A. Suk
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Antioxidants, 2023 The outer blood–retina barrier (oBRB), comprises tightly connected retinal pigment epithelium (RPE) cells, Bruch’s membrane, and choroid blood vessels, and is essential for retinal health and normal visual function.
Yali Niu +8 more
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Frontiers in Medicine, 2023 Macular edema is the pathological accumulation of fluid in the central retina. It is a complication of many retinal diseases, including diabetic retinopathy, retinal vascular occlusions and uveitis, among others.
Cameron D. Haydinger +3 more
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The Blood-Retinal Barriers [PDF]
British Journal of Ophthalmology, 1981 This text contains material from a series of lectures by distinguished scientists and clinicians who participated in the Advanced Study Institutes series on blood-retinal barriers that was held in Espinho, Portugal, in September 1979. The book is divided into the following parts: general aspects of membrane permeability; sites and functions of the ...
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Comparative transcriptome analysis of inner blood-retinal barrier and blood–brain barrier in rats
Scientific Reports, 2021 Although retinal microvessels (RMVs) and brain microvessels (BMVs) are closely related in their developmental and share similar blood-neural barriers, studies have reported markedly different responses to stressors such as diabetes.
Y. Li +5 more
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The blood-retinal barrier in angioid streaks [PDF]
Eye, 1988 The blood retinal barrier was investigated in a group of patients with angioid streaks and pseudoxanthoma elasticum, using the technique of vitreous fluorophotometry. Angioid streaks are breaks in the elastic layer of Bruch's membrane with atrophy of the adjacent pigment epithelium. The retinal pigment epithelial cells and their intercellular junctions
R, Brown, M F, Raines
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