Results 71 to 80 of about 86,370 (197)

Metabolic Deregulation of the Blood-Outer Retinal Barrier in Retinitis Pigmentosa

Cell Reports, 2019
Summary: Retinitis pigmentosa (RP) initiates with diminished rod photoreceptor function, causing peripheral and night-time vision loss. However, subsequent loss of cone function and high-resolution daylight and color vision is most debilitating.
Wei Wang, Ashwini Kini, Yekai Wang, Tingting Liu, Yao Chen, Eric Vukmanic, Douglas Emery, Yongqing Liu, Xiaoqin Lu, Lei Jin, San Joon Lee, Patrick Scott, Xiao Liu, Kevin Dean, Qingxian Lu, Enzo Fortuny, Robert James, Henry J. Kaplan, Jianhai Du, Douglas C. Dean   +19 more
doaj   +1 more source

Dietary fatty acids and lipoproteins on progression of age-related macular degeneration [PDF]

, 2017
Age-related macular degeneration (AMD) is a medical condition of central loss vision and blindness. Numerous studies have revealed that changes on certain dietary fatty acids (FAs) could have useful for AMD management.
Abia González, María del Rocío, Bermúdez Pulgarín, Beatriz, García Muriana, Francisco José, López Martín, Sergio, Montserrat de la Paz, Sergio, Naranjo Gutiérrez, María del Carmen   +5 more
core   +3 more sources

Optical coherence tomography: automatic retina classification through support vector machines [PDF]

, 2012
Optical coherence tomography (OCT) is becoming one of the most important imaging modalities in ophthalmology due to its non-invasiveness and by allowing the visualisation the human retina structure in detail.
Bernardes, Rui, Cunha-Vaz, José, Gonçalves, Valter, Santos, Torcato, Serranho, Pedro   +4 more
core  

Therapeutic potential of co-enzyme Q10 in retinal diseases [PDF]

, 2017
Coenzyme Q10 (CoQ10) plays a critical role in mitochondrial oxidative phosphorylation by serving as an electron carrier in the respiratory electron transport chain.
Marcheggiani, Fabio, Reilly, James, Shu, Xinhua, Tiano, Luca, Tohari, Ali Mohammad, Zhang, Xun, Zhou, Xinzhi   +6 more
core   +1 more source

Retinal endothelial cell phenotypic modifications during experimental autoimmune uveitis: a transcriptomic approach

BMC Ophthalmology, 2020
Background Blood-retinal barrier cells are known to exhibit a massive phenotypic change during experimental autoimmune uveitis (EAU) development. In an attempt to investigate the mechanisms of blood-retinal barrier (BRB) breakdown at a global level, we ...
Deborah A. Lipski, Vincent Foucart, Rémi Dewispelaere, Laure E. Caspers, Matthieu Defrance, Catherine Bruyns, François Willermain   +6 more
doaj   +1 more source

Retinal and Cortical Blood Flow Dynamics Following Systemic Blood-Neural Barrier Disruption

Frontiers in Neuroscience, 2017
To consider whether imaging retinal vasculature may be used as a marker for cortical vessels, we compared fluorescein angiography flow dynamics before and after pharmacological disruption of blood-neural barriers.
Flora Hui, Christine T. O. Nguyen, Zheng He, Algis J. Vingrys, Rachel Gurrell, Rebecca L. Fish, Bang V. Bui   +6 more
doaj   +1 more source

The Role of Systemic Antimicrobials in the Treatment of Endophthalmitis: A Review and an International Perspective

Ophthalmology and Therapy, 2020
Background The optimal management of patients with endophthalmitis is challenging and includes both intravitreal and, in some cases, systemic antimicrobials. Systemic antimicrobials may be administered either intravenously or orally.
Andrzej Grzybowski, Magdalena Turczynowska, Stephen G. Schwartz, Nidhi Relhan, Harry W. Flynn   +4 more
doaj   +1 more source

Self-assembled nanoparticles in ocular delivery: a comprehensive review

Discover Applied Sciences
Ocular nanoparticles are tiny particles designed to deliver drugs to the eye and have increased drug stability, prolonged drug release, and thereby enhanced bioavailability.
Shanmugam Saraswathi Tenpattinam, Sarad Pawar Naik Bukke, Praveen Kumar Kusuma, Hope Onohuean, Mohan Mothilal, Umasankar Krishnamaraju, Narayana Goruntla, Tadele Mekuriya Yadesa   +7 more
doaj   +1 more source

Role of Peoxisome Proliferator Activator Receptor 𝛾 on Blood Retinal Barrier Breakdown

PPAR Research, 2008
The retinal vessels have two barriers: the retinal pigment epithelium and the retinal vascular endothelium. Each barrier exhibits increased permeability under various pathological conditions.
Yasuo Yanagi
doaj   +1 more source

Novel rodent models for macular research [PDF]

, 2010
Background: Many disabling human retinal disorders involve the central retina, particularly the macula. However, the commonly used rodent models in research, mouse and rat, do not possess a macula.
Huber, Gesine, Heynen, Severin, Imsand, Coni, vom Hagen, Franziska, Muehlfriedel, Regine, Tanimoto, Naoyuki, Feng, Yuxi, Hammes, Hans-Peter, Grimm, Christian, Peichl, Leo, Seeliger, Mathias W., Beck, Susanne Christiane   +11 more
core   +1 more source