Results 141 to 150 of about 6,673,950 (317)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Blood [PDF]

A fiction novel using the magical realism style. This is more than just a time-travel novel - Blood is a far-reaching and multi-layered work that must be read to be believed.
Kay, Peter.
core  

Prioritization of Kidney Cell Types Highlights Myofibroblast Cells in Regulating Human Blood Pressure [PDF]

Introduction: Blood pressure (BP) is a highly heritable trait with over 2000 underlying genomic loci identified to date. Although the kidney plays a key role, little is known about specific cell types involved in the genetic regulation of BP.Methods ...
de Borst, Martin, International Consortium of Blood Pressure; Soroush Sardari, de Borst, M, Koskinen, Seppo, Sardari, S, Vaez, A, International Consortium of Blood Pressure, de Borst, Martin; id_orcid, Snieder, H, Gow, Alan J.; id_orcid, Snieder, Harold, ?, ?, Kamali, Z, Ganji-Arjenaki, M, Ganji-Arjenaki, Mahboube, Snieder, Harold; id_orcid, Kamali, Zoha; id_orcid, Sardari, Soroush, Vaez, Ahmad, Vaez, Ahmac, et al., Kamali, Zoha   +21 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Corrigendum: Predictors of high SARS-CoV-2 immunoglobulin G titers in COVID-19 convalescent whole-blood donors: a cross-sectional study in China

Frontiers in Immunology, 2023
Jingyun Tang, Humin Liu, Qing Wang, Xiaobo Gu, Jia Wang, Wenjun Li, Yinglan Luo, Yan Li, Lan Deng, Yue Luo, Xinman Du, Donglin Tan, Xuemei Fu, Xue Chen   +13 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Retrospective study on transfusion-related acute lung injury after intraoperative and postoperative blood transfusion in patients at a single medical center

BMC Pulmonary Medicine
Introduction Transfusion-related acute lung injury (TRALI) is a life-threatening syndrome that occurs within six hours of a blood transfusion.
Jing Liu, Xin Ye, Huaqin Liang, Shuangfeng Xie, Yanhong Chen, Dawei Chen, Jing Deng, Xiuzhang Xu, Haoqiang Ding, Yangkai Chen, Wenjie Xia, Yili Zhao   +11 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Collection of Fetal Blood for Stem Cell Research and Therapy [PDF]

, 2006
Stem cell research has generated novel therapeutic opportunities at the expense of new ethical and legal problems. Its promoters recommended early clamping of the umbilical cord to maximize the amount of acquired fetal blood.
Portuondo, N., Varadi, V., Ende, N., Iffy, L.   +3 more
core  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source