Results 181 to 190 of about 5,245,204 (269)

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

Chronic Non-Communicable Disease Burden among Recently Arrived Refugees in Syracuse, New York. [PDF]

Ann Glob Health
Wu E, Searles M, Taiwo I, Campagna CD, Kuroda M, Shaw AV.   +5 more
europepmc   +1 more source

In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans

FEBS Open Bio, EarlyView.
In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller, Jana Bleher, Birgit Weinberger, Lourdes Rocamora‐Reverte   +3 more
wiley   +1 more source

Blood and Urine Transcriptomes Reveal Complementary Host Responses and a Creatinine-Associated Urinary Transcriptional Axis in Sepsis. [PDF]

Diagnostics (Basel)
Beloussov V, Strochkov V, Sandybayev N, Lavrinenko A, Aitpenov T, Solomadin M.   +5 more
europepmc   +1 more source

Ultrafast visual detection of Streptococcus suis via HtpsC‐targeted LAMP–CRISPR–Cas12a coupled with lateral flow immunochromatography

FEBS Open Bio, EarlyView.
A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li, Miao Xin, Xiao‐wen Cui, Shi‐yin Yu, Fei Meng, Min Cao, Xiao‐hui Xiong, Yi‐chen Lu   +7 more
wiley   +1 more source

Longitudinal blood pressure trajectories and time to stroke among hypertensive patients: A Bayesian multivariate joint modeling study in Benishangul-Gumuz, Ethiopia. [PDF]

PLoS One
Assefa SK, Tadesse K, Yenus S, Tegene T, Bekeko SD, Abegaz HM, Endalemew SG, Feleke DB, Bemgako AB, Gobena AE, Redi BA, Asgedom DK.   +11 more
europepmc   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Early BMI-associated increases in central and peripheral blood pressure in primary school children: evidence of a continuous, nonlinear relationship below the overweight threshold. [PDF]

Eur J Pediatr
von der Born J, Wilmsmeier L, Sugianto RI, Grabitz C, Ubenauf TA, Lehmann E, Memaran N, Braun AC, Homeyer D, Tegtbur U, Schmidt BMW, Melk A.   +11 more
europepmc   +1 more source