Results 41 to 50 of about 733,473 (339)

Ask a pathologist [PDF]

open access: yes, 2017
This article answers the question: Our hospital blood bank has started using platelet additive solution (PAS) platelets and psoralen treated platelets.
Coberly, Emily
core   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Trend in seroprevalence of Hepatitis B virus infection among blood donors of coastal Karnataka, India

open access: yesJournal of Infection in Developing Countries, 2009
Background: Hepatitis B is one of the transfusion transmissible infections. The prevalence of this infection varies across the different geographies. Noting the trend in seroprevalence is useful to assist the preventive strategies.
Karandeep Singh   +2 more
doaj   +1 more source

A rational framework for production decision making in blood establishments [PDF]

open access: yes, 2012
SAD_BaSe is a blood bank data analysis software, created to assist in the management of blood donations and the blood production chain in blood establishments. In particular, the system keeps track of several collection and production indicators, enables
Lourenço, Anália   +2 more
core   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Bioinformatics analysis of HBV s gene mutation in blood donor

open access: yesZhongguo shuxue zazhi
Objective To analyze the infectious indicators, HBV s gene mutations and changes in bioinformatics characteristics of HBV DNA+ /HBsAg- blood donor. Methods A sample of HBV DNA+ /HBsAg- was screened by PCR method, and HBsAg/HBsAb/HBeAg/HBeAb/HBcAb of HBV ...
Jiacheng FAN   +4 more
doaj   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

Vale Jiří Rondiak : 1934 – 2013 [PDF]

open access: yes, 2014
Jiří Rondiak, an eminent Czech physician and specialist in blood transfusion died in September 2013 after a long illness. Rondiak was born in 1934 in Hořice v Podkrkonoší, a small East Bohemian town where is father was a renowned and loved general ...
Farrugia, Albert
core  

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Transfusion Problems in Hemolytic Anemias [PDF]

open access: yes, 1970
In this presentation I have attempted to present some of the transfusion problems that face the Blood Bank and the physician treating the patient. I have briefly discussed methods of recognizing the complicating factors, interpretation of their clinical ...
Hossaini, Ali A.
core   +1 more source

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