Results 41 to 50 of about 779,380 (305)

Distributed simulation with COTS simulation packages: A case study in health care supply chain simulation [PDF]

, 2006
The UK National Blood Service (NBS) is a public funded body that is responsible for distributing blood and asso-ciated products. A discrete-event simulation of the NBS supply chain in the Southampton area has been built using the commercial off-the-shelf
Brailsford, S, Katsaliaki, K, Mustafee, N, Taylor, S J E   +3 more
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Trend in seroprevalence of Hepatitis B virus infection among blood donors of coastal Karnataka, India

Journal of Infection in Developing Countries, 2009
Background: Hepatitis B is one of the transfusion transmissible infections. The prevalence of this infection varies across the different geographies. Noting the trend in seroprevalence is useful to assist the preventive strategies.
Karandeep Singh, Sudha Bhat, Shamee Shastry   +2 more
doaj   +1 more source

Transfusion Problems in Hemolytic Anemias [PDF]

, 1970
In this presentation I have attempted to present some of the transfusion problems that face the Blood Bank and the physician treating the patient. I have briefly discussed methods of recognizing the complicating factors, interpretation of their clinical ...
Hossaini, Ali A.
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Blood Donor Serological Screening in Makkah, Saudi Arabia: A 7-Year Retrospective Study on Transfusion-Transmitted Infections

International Journal of Microbiology
Conclusion: The overall prevalence of TTIs among blood donors in Makkah was low, affirming the effectiveness of current screening protocols. However, the relatively high prevalence of hepatitis B core antibodies indicates prior exposure among a notable ...
Amr J. Halawani, Afnan J. Hawsawi, Latifa A. Jaber, Saeed M. Kabrah, Turki M. Maghrabi, Khaled M. Alobaid, Alaa A. Kaki, Ayman M. Aljabri, Adel S. Alsaedi, Mohammed M. Alharbi, Abdullah F. Alhazmi, Hani A. Alsaedi, Ahmed S. Almalki, Fatima A. Alharthi, Yahya H. Almalki, Abdullah M. Alotaibi, Rakan M. Abu-Harba, Ahmad F. Arbaeen, Hesham A. Malak, Mohammad O. Sabbag, Rani O. Alnabati   +20 more
doaj   +1 more source

Bioinformatics analysis of HBV s gene mutation in blood donor

Zhongguo shuxue zazhi
Objective To analyze the infectious indicators, HBV s gene mutations and changes in bioinformatics characteristics of HBV DNA+ /HBsAg- blood donor. Methods A sample of HBV DNA+ /HBsAg- was screened by PCR method, and HBsAg/HBsAb/HBeAg/HBeAb/HBcAb of HBV ...
Jiacheng FAN, Qing LI, Xiuli CHEN, Shixiang LIU, Ye CHEN   +4 more
doaj   +1 more source

Foci of Schistosomiasis mekongi, Northern Cambodia: II. Distribution of infection and morbidity. [PDF]

, 1999
In the province of Kracheh, in Northern Cambodia, a baseline epidemiological survey on Schistosoma mekongi was conducted along the Mekong River between December 1994 and April 1995. The results of household surveys of highly affected villages of the East
Biays, S, Legros, P, Lormand, J D, Ly, C S, Men, C, Odermatt, P, Philips, M, Saem, C, Sokha, K, Stich, A H, Tanner, M   +10 more
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source