Results 211 to 220 of about 4,957,945 (327)

Adaptive Machine Learning for Electronic Nose‐Based Forensic VOC Classification

open access: yesAdvanced Science, EarlyView.
A 32‐element electronic nose enhanced with machine learning demonstrates exceptional accuracy in differentiating between living and deceased individuals (98.1%), discriminating human and animal specimens (97.2%), and estimating postmortem intervals.
Ivan Shtepliuk   +3 more
wiley   +1 more source

Gut Parabacteroides distasonis‐derived Indole‐3‐Acetic Acid Promotes Phospholipid Remodeling and Enhances Ferroptosis Sensitivity via the AhR‐FASN Axis in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
Indole‐3‐acetic acid (3‐IAA) derived from gut P. distasonis binds to AhR in bladder cancer cells and downregulates FASN transcription, thereby increasing sensitivity to ferroptosis and suppressing the development of bladder tumors. Specifically, 3‐IAA treatment leads to an increase in the proportion of PC/PE‐PUFAs and a decrease in the proportions of ...
Weijia Li   +16 more
wiley   +1 more source

Lysosomal Cathepsin S Escape Facilitates Near Infrared Light‐Triggered Pyroptosis Via an Antibody‐Indocyanine Green Conjugate

open access: yesAdvanced Science, EarlyView.
ICAM1 antibody‐bound ICG triggers tumor‐specific, caspase‐1‐independent pyroptosis via CTSS‐mediated GSDMD cleavage, activates antitumor immunity, and synergizes with anti–PD‐1 therapy, offering a non‐apoptotic strategy to overcome resistance in cancer treatment.
Fan Chen   +17 more
wiley   +1 more source

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

open access: yesAdvanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen   +6 more
wiley   +1 more source

Therapeutic Repair of Sperm Quality Decline Caused by Polytetrafluoroethylene

open access: yesAdvanced Science, EarlyView.
Exposure to PTFE (teflon), a commonly used microplastic in non‐stick cookware, significantly reduces sperm quality in both humans and mice. Specifically, PTFE induces the disruption of sperm cytoskeleton and F‐actin assembly through targeting SKAP2 in haploid spermatid.
Shiming Gan   +15 more
wiley   +1 more source

Evaluation of surrogate markers for human immunodeficiency virus infection among blood donors at the blood bank of "Hospital Universitário Regional Norte do Paraná", Londrina, PR, Brazil [PDF]

open access: green, 2003
Reiche Edna Maria Vissoci   +7 more
openalex  

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