Results 221 to 230 of about 4,957,945 (327)
Ovarian cancer patients with high levels of mortalin protein in their tumors have worse survival. The investigational drug SHetA2 interferes with mortalin's support of mitochondria. The resulting mitochondrial damage causes a process called mitophagy that contributes to how SHetA2 kills cancer cells. Noncancerous cells repair their mitochondria through
Vishal Chandra+9 more
wiley +1 more source
Noninvasive and sensitive detection of tau protein dynamics across developmental stages and APOE genotypes remain a challenge in Alzheimer's disease (AD) research. This study reveals the dynamics of tau secretion in label‐free manner using surface‐enhanced Raman spectroscopy (SERS) and human cerebral organoids (hCOs). This study provides novel insights
Yongjae Jo+11 more
wiley +1 more source
SAD_BaSe: A Blood Bank Data Analysis Software [PDF]
Augusto Ramoa+2 more
openalex +1 more source
The Role of CAF‐derived Vitronectin in Promoting Colorectal Cancer Progression and Immunosuppression
Cancer‐associated fibroblast (CAF)‐derived VTN upregulates SLC6A8 expression in colorectal cancer (CRC) cells and macrophages through enhanced FAK phosphorylation. This modulation significantly increases the cellular uptake of creatine and ATP, promoting cancer progression and macrophage polarization.
Jiahua Yu+5 more
wiley +1 more source
Plasma metabolic detection combined with machine learning offers a precise (area under the curve of 0.874) and high‐throughput (<30 s) diagnosis for pathologic myopia (serious myopic macular degeneration). The biomarkers indicate the pathologic myopia‐associated systemic metabolic reprogramming, which exhibits specificity for myopic macular ...
Ziheng Qi+13 more
wiley +1 more source
Using microfluidic models of capillary networks, this study discovered that fluid shear stresses on circulating tumor cells transiting through capillary‐sized bifurcations shed a novel class of shear‐dependent large extracellular vesicle, “shearosomes”, whose proteome comprises of over 3000 distinct proteins.
Angelos Vrynas+16 more
wiley +1 more source
Bacterial contaminants of stored blood and blood components ready for transfusion at blood banks in Mekelle, Northern Ethiopia. [PDF]
Agzie M+4 more
europepmc +1 more source
Blood and Tissue Bank for Study of Giant Cell Arteritis
Bradley J. Katz
openalex +1 more source