Results 61 to 70 of about 7,457,927 (294)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Effects of hydroalcoholic extract of celery (apium graveolens) seed on blood & biochemical parameters of adult male rats

open access: yesKufa Journal for Veterinary Medical Sciences, 2016
Targeted research study the effect hydroalcoholic extract of celery (apium graveolens) seed on blood & biochemical parameters of  adult male rats. Twenty-four  adult male rats, were randomly divided into three equal groups.
Masar Jabbar Jary Al-Kurdy
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Natural pomegranate juice reduces inflammation, muscle damage and increase platelets blood levels in active healthy Tunisian aged men

open access: yesAlexandria Journal of Medicine, 2018
Currently, it’s well established that aging is associated with various health problems that may interfere with the maintenance of a good nutritional status. Otherwise, pomegranate (POM) was shown to prevent or treat various disease risk factors in adults.
Ammar Achraf   +7 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

Effect of Blood Storage on Biochemical Parameters Assessed at Periodic Intervals in CPDA1 Blood Bags [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2018
Introduction: Blood when stored at 4°C, effectuates alterations in biochemical and mechanical properties of red blood cells because of storage conditions, which are called as storage lesions.
Ujwal B Upadya   +2 more
doaj   +1 more source

The influence of genetic factors on blood biochemical parameters in pigs. [PDF]

open access: yes, 2014
The aim of this research - to analyze the influence of genetic factors on blood biochemical parameters in pigs. In this work was analyzed blood biochemical parameters impact from pigs breed and gender.
Smilgevičiūtė, Simona,
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Effects of Fermented Wheat Bran on Blood Biochemical Parameters and Carcass Characteristics of Broiler Birds

open access: yesInternational Journal of Bio-Resource and Stress Management, 2023
The experiment was conducted during 5th September 17th October, 2022 (42 Days) in the Department of Veterinary Microbiology and Immunology, College of Veterinary Sciences and Animal Husbandry, Central Agricultural University, Selesih, Aizawl, Mizoram ...
Akash Paul   +5 more
doaj   +1 more source

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