Results 151 to 160 of about 1,992,807 (367)

CD44v, S1PR1, HER3, MET and cancer‐associated amino acid transporters are promising targets for the pancreatic cancers characterized using mAb

open access: yesFEBS Open Bio, EarlyView.
Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano   +16 more
wiley   +1 more source

The lymphocyte levels of Hashimoto thyroiditis patients were significantly lower than that of healthy population

open access: yesFrontiers in Endocrinology
Background and purposeHashimoto thyroiditis (HT) is an autoimmune disease without infectivity. We compared the differences of blood lymphocytes levels between HT patients and healthy people.Patients and methodsThis study included a total of 84 HT ...
Hui Xue, Ruyi Xu
doaj   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

open access: yesFEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy   +14 more
wiley   +1 more source

Subclinical leukopenia in a cross section of Nigerian blood donors

open access: yesJournal of Blood Medicine, 2011
Zaccheaus A Jeremiah1, Ruth E Umoh2, Teddy C Adias31Haematology and Blood Transfusion Science Unit, Department of Medical Laboratory Sciences, College of Health Sciences, Niger Delta University, Bayelsa State, Nigeria; 2Department of Haematology and ...
Adias TC, Umoh RE, Jeremiah ZA
doaj  

Tryptophan‐sensing receptor GPR142 expression levels are directly regulated by proinflammatory cytokines in ghrelin‐producing cells

open access: yesFEBS Open Bio, EarlyView.
GPR142, a tryptophan‐sensing receptor, stimulates gastrointestinal hormones like ghrelin and is linked to inflammation regulation. Proinflammatory cytokines suppress ghrelin production, while tryptophan levels decrease via IDO1 activation. Our findings reveal that proinflammatory cytokines directly regulate GPR142 expression in ghrelin‐producing cells,
Yoko Ueda   +15 more
wiley   +1 more source

Total White Blood Cell Count, Differential White Blood Cell Count and the Odds of Prostate Cancer

open access: yes, 2015
Abstract Introduction The objective of this analysis was conducted to examine the association between total white blood cell (WBC) count, differential WBC count and the odds of prostate cancer (PCa) prevalence. Methods A cross-sectional analysis of 2,583 men, ages 20 to 80 years, from the 2009-2010 National Health and Nutrition Examination Survey was ...
openaire   +2 more sources

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