A potential tumor suppressor role of PLK2 in glioblastoma
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia+5 more
wiley +1 more source
Differences in Total White Blood Cell Counts and Absolute Neutrophil Counts between Very Low Birth Weight African American and Caucasian Neonates [PDF]
Jack Guida+3 more
openalex +1 more source
Exploring Few-Shot Object Detection on Blood Smear Images: A Case Study of Leukocytes and Schistocytes [PDF]
The detection of blood disorders often hinges upon the quantification of specific blood cell types. Variations in cell counts may indicate the presence of pathological conditions. Thus, the significance of developing precise automatic systems for blood cell enumeration is underscored. The investigation focuses on a novel approach termed DE-ViT.
arxiv
Identification of inhibitors of the Salmonella FraB deglycase, a drug target
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law+6 more
wiley +1 more source
Pulmonary Colonization with Pneumocystis cariniiin Human Immunodeficiency Virus-Negative Patients: Assessing Risk with Blood CD4+ T Cell Counts [PDF]
Gilles Nevez+4 more
openalex +1 more source
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma+3 more
wiley +1 more source
Influence of preoperative complete blood cell counts on surgical outcomes in healthy horses: 102 cases (1986–1996) [PDF]
Anne Rosemarie Toews, John Campbell
openalex +1 more source
Bacterial Infection and Hematological Parameters of aborted women in Thi-Qar province, Iraq
The Current study was performed among 40 aborted women whom referred Bint-AL Huda teaching hospital in Thi-Qar province, Iraq. During the period from August 2012 to April 2013.
Qasim Hassan Wdaa
doaj
Hydrogen sulfide repairs testicular damage induced by heat stress in rats
Heat stress can cause testicular damage and affect fertility. We investigated the potential protective role of hydrogen sulfide (H2S) against heat stress‐induced testicular injury and observed that H2S donor NaHS can effectively restore testicular damage in rats by inhibiting inflammation and oxidative stress. Our results suggest that H2S might be used
Xinyu Guo+6 more
wiley +1 more source