Results 91 to 100 of about 9,259,664 (317)

Blocking TLR7- and TLR9-mediated IFN-α Production by Plasmacytoid Dendritic Cells Does Not Diminish Immune Activation in Early SIV Infection [PDF]

, 2013
Persistent production of type I interferon (IFN) by activated plasmacytoid dendritic cells (pDC) is a leading model to explain chronic immune activation in human immunodeficiency virus (HIV) infection but direct evidence for this is lacking.
Simon C Watkins, Normolle, D, Kader, M, Elizabeth R Wonderlich, Guiducci, C, Smith, Amanda P., Watkins, SC, Amanda P. Smith (437248), Normolle, Daniel, Watkins Simon C., Franck J. Barrat (437251), Smith Amanda P., Simon M Barratt-Boyes, Daniel Normolle, Daniel Normolle (437250), Barrat Franck J., Simon M. Barratt-Boyes (264203), Normolle Daniel, Wonderlich Elizabeth R., Franck J Barrat, Barratt-Boyes Simon M., Guiducci, Cristiana, Barrat, Franck J., Kader, Muhamuda, Guiducci Cristiana, Wonderlich, ER, Cristiana Guiducci, Barrat, FJ, Watkins, Simon C., Amanda P Smith, Barratt-Boyes, SM, Muhamuda Kader, Smith, AP, Wonderlich, Elizabeth R., Cristiana Guiducci (437249), Simon C. Watkins (39900), Barratt-Boyes, Simon M., Muhamuda Kader (437247), Elizabeth R. Wonderlich (270792), Kader Muhamuda   +39 more
core   +2 more sources

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto   +9 more
wiley   +1 more source

Renal Findings in Patients with Thalassemia at Abdominal Ultrasound: Should We Still Talk about “Incidentalomas”? Results of a Long-Term Follow-Up

Diagnostics
We retrospectively collected all ultrasound imaging data of our thalassemia patients over a period of 10 years with the aim of assessing the prevalence and the risk factors of renal stones and cysts.
Carmina Fatigati, Antonella Meloni, Silvia Costantini, Anna Spasiano, Flora Ascione, Filippo Cademartiri, Paolo Ricchi   +6 more
doaj   +1 more source

Production of Transfusable Red Blood Cells from Stem Cells [PDF]

, 2017
Blood transfusion is a well-established cell therapy. However, blood available for transfusion is a limited resource and is available only through donations by healthy volunteers.
김현옥
core   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

ABI3BP promotes renal aging through Klotho-mediated ferroptosis

Journal of Translational Medicine
The aging process of the kidneys is accompanied with several structural diseases. Abnormal fiber formation disrupts the balance of kidney structure and function, causing to end-stage renal disease and subsequent renal failure.
Ren Ji, Lin Wei, Yuxin Zan, Xiao Li, Shinan Ma, Liming Ma, Xiju He, Li Wang, Yan Ding   +8 more
doaj   +1 more source

Immunoglobulin-secreting cells in cord blood: effects of Epstein-Barr virus and interleukin-4

, 2009
To access publisher full text version of this article. Please click on the hyperlink in Additional Links fieldThe contribution of cord blood B lymphocytes to the immune response has been under considerable investigation. Cord blood B cells produce almost
Thorsteinsson, L, Gudmundsson, K O, Gudmundsson, S, Haraldsson, A   +3 more
core   +1 more source

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

ANGPTL8 accelerates bone loss in diabetic mice by promoting osteoclastic differentiation and inhibiting osteoblastic differentiation through AMPK pathway-mediated metabolic reprogramming

Cellular and Molecular Life Sciences
Disruptions in energy metabolism within skeletal cells play a critical role in the pathogenesis of diabetic osteoporosis (DOP), primarily by affecting bone’s metabolic balance.
Peng Tuo, Wenbo Mu, Xinyu Bai, Suyin Wang, Liang Hu, Yining Xu, Ruopu Mao, Yixiang Liu, Yahong Yuan, Qiufang Zhang, Xingrong Guo, Shinan Ma, Xiaoli Wang   +12 more
doaj   +1 more source