Results 61 to 70 of about 2,454,570 (173)

Generation of induced pluripotent stem cell line derived from FNAIT patient with CD36 deficiency mutations

open access: yesStem Cell Research, 2022
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) caused by anti-CD36 isoantibodies is a common disease and the frequency of type I CD36 deficiency is relatively high in eastern Asian populations. Currently, patient-specific induced pluripotent stem
Dawei Chen   +5 more
doaj  

A Simulation of Blood Cells in Branching Capillaries [PDF]

open access: yesarXiv, 2008
The multi-cellular hydrodynamic interactions play a critical role in the phenomenology of blood flow in the microcirculation. A fast algorithm has been developed to simulate large numbers of cells modeled as elastic thin membranes. For red blood cells, which are the dominant component in blood, the membrane has strong resistance to surface dilatation ...
arxiv  

Oscillations in a maturation model of blood cell production [PDF]

open access: yesarXiv, 2004
In this paper we use a continuous model to describe the development of a single cell lineage following the committal of stem cells. Three separate controls are implemented in the model, namely the proliferative control of stem cells, the proliferative control of developing blast cells, and the peripheral control of stem cell committal by circulating ...
arxiv  

Multi-omics approaches reveal that diffuse midline gliomas present altered DNA replication and are susceptible to replication stress therapy

open access: yesGenome Biology
Background The fatal diffuse midline gliomas (DMG) are characterized by an undruggable H3K27M mutation in H3.1 or H3.3. K27M impairs normal development by stalling differentiation.
Anastasia E. Hains   +11 more
doaj   +1 more source

Identification of Biomarkers Driving Blood Cell Development [PDF]

open access: yesarXiv, 2019
A blood cell lineage consists of several consecutive developmental stages from the pluripotent or multipotent stem cell to a particular stage of terminally differentiated cells. There is considerable interest in identifying the key regulatory genes that govern blood cell development from the gene expression data without considering the underlying ...
arxiv  

Comparative Analysis of Red Blood Cells, White Blood Cells, Platelet Count, and Indices in Type 2 Diabetes Mellitus Patients and Normal Controls: Association and Clinical Implications

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2023
Khaled Essawi,1 Gasim Dobie,1 Misk F Shaabi,1 Waleed Hakami,1 Muhammad Saboor,2 Aymen M Madkhali,1 Abdullah AH Hamami,3 Wael H Allallah,3 Mohammad S Akhter,1 Abdullah A Mobarki,1 Hassan A Hamali1 1Department of Medical Laboratory Technology, College of ...
Essawi K   +10 more
doaj  

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