Results 61 to 70 of about 9,259,664 (317)

Ex vivo rapamycin treatment of human cord blood CD34+ cells enhances their engraftment of NSG mice [PDF]

, 2011
Since cord blood (CB) has become a commonly used source of transplantable hematopoietic stem (HSC) and hematopoietic progenitor cells (HPC), there has been a need to overcome the limited HSC and HPC numbers available to transplant from a single CB ...
Hangoc, Giao, Timothy B. Campbell, Sara L. Rohrabaugh, Rohrabaugh, Sara L., Giao Hangoc, Broxmeyer, Hal E., Hal E. Broxmeyer, Campbell, Timothy B.   +7 more
core   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

A Blood Bank Standardized Production of Human Platelet Lysate for Mesenchymal Stromal Cell Expansion: Proteomic Characterization and Biological Effects

Frontiers in Cell and Developmental Biology, 2021
Human platelet lysate (hPL) is considered a valid substitute to fetal bovine serum (FBS) in the expansion of mesenchymal stromal cells (MSC), and it is commonly produced starting from intermediate side products of whole blood donations.
Andrea Bianchetti, Clizia Chinello, Michele Guindani, Simona Braga, Arabella Neva, Rosanna Verardi, Giovanna Piovani, Lisa Pagani, Gina Lisignoli, Fulvio Magni, Domenico Russo, Camillo Almici   +11 more
doaj   +1 more source

Imaging morphological details and pathological differences of red blood cells using tapping-mode AFM [PDF]

, 2004
The surface topography of red blood cells (RBCs) was investigated under nearphysiological conditions using atomic force microscopy (AFM). An immobilization protocol was established where RBCs are coupled via molecular bonds of the membrane glycoproteins ...
Zhu, Rong, Gruber, Hermann J., Stroh, Cordula M., Berg, Jörg, Ebner, A., Rankl, Christian, Kamruzzahan, A. S. M., Huss, Ralf, Hinterdorfer, Peter, Kienberger, Ferry   +9 more
core   +1 more source

Biphasic Clinical Course of Pediatric Cytomegalovirus‐Associated Immune Thrombocytopenia: Early Poor Treatment Response but Favorable Long‐Term Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cytomegalovirus (CMV) is a recognized trigger of immune thrombocytopenia (ITP); however, its incidence and impact on disease course in children remain controversial. Therefore, we aimed to characterize the clinical course of pediatric patients with CMV‐associated ITP.
Oded Gilad, Ohad Atia, Osama Tanous, Dafna Brik Simon, Michal Dvori, Miriam Cohen, Tracie A. Goldberg, Efraim Bilavsky, Joanne Yacobovich, Orna Steinberg‐Shemer   +9 more
wiley   +1 more source

Microfluidic Systems for Blood and Blood Cell Characterization

Biosensors, 2022
A laboratory blood test is vital for assessing a patient’s health and disease status. Advances in microfluidic technology have opened the door for on-chip blood analysis. Currently, microfluidic devices can reproduce myriad routine laboratory blood tests.
Hojin Kim, Alexander Zhbanov, Sung Yang
openaire   +3 more sources

Keratin 8 enhances the efficacy of mesenchymal stem cells in preventing acute graft-versus-host disease

Chinese Medical Journal
. Background:. Acute graft-versus-host disease (aGVHD) remains a leading cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (allo-HSCT). The development of methods that preserve graft-versus-leukemia (GVL) activity
Ya Zhou, Rui Wang, Zheng Wang, Hao Yu, Qing Xu, Yuxi Xu, Yuxuan He, Ziyi Hu, Qi Wang, Xiaodong Xie, Shijie Yang, Lingyu Zeng, Xiaoqi Wang, Qingxiao Song, Xi Zhang, Yanjie Yin   +15 more
doaj   +1 more source

The Effects of ATO on Mitochondria Apoptosis Pathway Genes Expression in APL Cell Line

Asian Pacific Journal of Cancer Biology, 2016
Purpose and Background: Acute promyelocystic leukemia is the most malignant acute leukemia that leads to death in few weeks. It constitutes 10-15% of acute myelocystic leukemia.
Maede Sharifizadeh, Kimia Davarian, Mehrdad Hashemi, Majid Momeni, Kamran Ali Moghdam, Ardeshir Ghavamzadeh, Hamidollah Ghafari, Abolfazl Movafagh   +7 more
doaj   +1 more source

Freeze-thaw lysates of P. falciparum-infected red blood cells induce differentiation of functionally competent regulatory T cells from memory T cells. [PDF]

, 2012
: In addition to naturally occurring regulatory T (nTreg) cells derived from the thymus, functionally competent Treg cells can be induced in vitro from peripheral blood lymphocytes in response to T-cell receptor stimulation with cytokine co-stimulation ...
Finney, OC, Walther, M, Riley, EM, Gray, AP, Lawrence, E, Njie, M   +5 more
core   +1 more source

The maturation of reticulocytes. II. Life-span of red cells originating from stress reticulocytes [PDF]

, 1975
Life-spans of macroreticuloytes and macrocytic red cells were studied. Rabbits were made anemic by injecting phenylhydrazine. Peripheral blood rich in reticulocytes was drawn, labeled with 3H-amino acids, and injected back into the anemic animal ...
Shimada, Atsuko
core   +1 more source