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Erythrocytes and Blood Coagulation [PDF]
Thrombosis and Haemostasis, 1974 SummaryThe action of intact and hemolyzed red cells in in vitro clotting systems is analyzed against the background of the clinical manifestations of red cell procoagulants in incompatible transfusions and hemolytic anemias in man and in experimental animals.
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Prostacyclin and Blood Coagulation
Drugs, 1981Prostacyclin is a potent but unstable vasodilator, and inhibitor of platelet aggregation, which is produced by blood vessel walls. Platelet aggregability may be constantly conditioned in vivo by local or circulating prostacyclin. Prostacyclin is important in the maintenance of vascular homeostasis and may be implicated in certain disease states.
J. R. Vane, S. Moncada
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Regulation of blood coagulation
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 2000The protein C anticoagulant pathway converts the coagulation signal generated by thrombin into an anticoagulant response through the activation of protein C by the thrombin-thrombomodulin (TM) complex. The activated protein C (APC) thus formed interacts with protein S to inactivate two critical coagulation cofactors, factors Va and VIIIa, thereby ...
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The Coagulation of Blood and Hemostasis
Annual Review of Physiology, 1950Since the number of papers on coagulation has greatly in creased, the reviewer, in order to avoid merely cataloging them with telegraphic brevity, was compelled to select mainly those which contribute specifically to the physiology of blood clotting.
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Mutation in blood coagulation factor V associated with resistance to activated protein C
Nature, 1994R. Bertina +7 more
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American Journal of Obstetrics and Gynecology, 1987
Blood coagulation consists of several interrelated reactions involving platelets and blood vessels, the classical cascade, and the fibrinolytic system. There is a complex of inhibiting influences on each of these schemes, and there are interrelationships among these inhibitory influences.
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Blood coagulation consists of several interrelated reactions involving platelets and blood vessels, the classical cascade, and the fibrinolytic system. There is a complex of inhibiting influences on each of these schemes, and there are interrelationships among these inhibitory influences.
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