Results 71 to 80 of about 26,639 (274)

Migraine and vascular disease biomarkers: A population-based case-control study. [PDF]

, 2018
Background The underpinnings of the migraine-stroke association remain uncertain, but endothelial activation is a potential mechanism. We evaluated the association of migraine and vascular disease biomarkers in a community-based population.
Ferrari, Michel D., Herial, Nabeel, Khubchandani, Jagdish, Koppen, Hille, Kruit, Mark C., Launer, Lenore J., Palm-Meinders, Inge H., Terwindt, Gisela M., Tietjen, Gretchen E., van Buchem, Mark A.   +9 more
core   +2 more sources

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Effect of DNA methylation on inhibitor development in people with hemophilia A treated with FVIII concentrates

Research and Practice in Thrombosis and Haemostasis
Background: Hemophilia A (HA) is a hereditary X-linked hemorrhagic disorder. Following the first treatment with exogenous factor (F)VIII, one-third of patients with severe HA develop anti-FVIII antibodies (inhibitors), which render treatment ineffective.
Himani Chand, Shermarke Hassan, Andrea Cairo, Roberta Palla, Flora Peyvandi, Flora Peyvandi, Pier M. Mannucci, Isabella Garagiola, Amal El-Beshlawy, Mohsen Elalfy, Vijay Ramanan, Peyman Eshghi, Suresh Hanagavadi, Ramabadran Varadarajan, Mehran Karimi, Mamta V. Manglani, Cecil Ross, Guy Young, Tulika Seth, Shashikant Apte, Dinesh M. Nayak, Elena Santagostino, Maria Elisa Mancuso, Adriana C. Sandoval Gonzalez, Johnny N. Mahlangu, Santiago Bonanad Boix, Monica Cerqueira, Nadia P. Ewing, Christoph Male, Tarek Owaidah, Veronica Soto Arellano, Nathan L. Kobrinsky, Suvankar Majumdar, Rosario Perez Garrido, Anupam Sachdeva, Mindy Simpson, Mathew Thomas, Ezio Zanon, Bulent Antmen, Kaan Kavakli, Marilyn J. Manco-Johnson, Monica Martinez, Esperanza Marzouka, Maria G. Mazzucconi, Daniela Neme, Angeles Palomo Bravo, Rogelio Paredes Aguilera, Alessandra Prezotti, Klaus Schmitt, Brian M. Wicklund, Bulent Zulfikar, Frits R. Rosendaal   +51 more
doaj   +1 more source

A Perspective of Coagulation Dysfunction in Multiple Sclerosis and in Experimental Allergic Encephalomyelitis [PDF]

, 2018
A key role of both coagulation and vascular thrombosis has been reported since the first descriptions of multiple sclerosis (MS). Subsequently, the observation of a close concordance between perivascular fibrin(ogen) deposition and the occurrence of ...
Adams, Adams, Akassoglou, Akassoglou, Akenami, Akenami, Albright, Alizadeh, Alonso, Amor, Antoniak, Beggs, Bidot, Bitsch, Boesen, Brkic, Bronstein, Brunetti, Castellino, Cesarman-Maus, Chapman, Chelmicka-Szorc, Claudio, Compston, Coughlin, Cuzner, Danø, Davalos, Davalos, Davidson, Davie, De Luca, Dekaban, Deschepper, Donovan, East, Ed Rainger, Engelmann, Esmon, Esmon, Fan, Fan, Farber, Feldman, Ferguson, Festoff, Field, Fiorini, Flick, Fog, Friedman, Garcia-Monco, García, Garg, Genc, Gloor, Griffin, Griffin, Guenther, Gveric, Göbel, Göbel, Göbel, Hafler, Han, Horstman, Huszak, Inaba, Inoue, Iong, Jacob, Jones, Kalaria, Kirichuk, Kirk, Kirk, Knauer, Koudriavtseva, Koudriavtseva, Koudriavtseva, Koudriavtseva, Kreutzberg, Kuhlmann, Kwon, Lane, Langer, Lassmann, Lassmann, Lassmann, Lesny, Liddelow, Lider, Lin, Lin, Lock, Lu, Mahmood, Mandoj, Marik, Mechelli, Miranda, Moll, Murray, Park, Parsons, Paterson, Perez, Persson, Persson, Petersen, Phillips, Pike, Plantone, Plumb, Putnam, Putnam, Rand, Reese, Reinhard, Roizin, Ryu, Ryu, Saberi, Savitky, Seeds, Seeds, Sheremata, Simón, Smith, Sobel, Soon, Sotnikov, Spadaro, Starossom, Starossom, Stavrou, Stolz, Teesalu, Tennent, Ugarova, Uzawa, van der Poll, Varga, Verrall, Wachowicz, Wakefield, Weisel, Whitlock, Wittinghofer, Wolter, Wright, Xue, Yadav, Yamaji, Yates, Yuksel, Zhang, Ziliotto, Zivadinov   +158 more
core   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

Advanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang, He Huang, Hongliang Dong, Qiang Ma, Hongyan Jin   +4 more
wiley   +1 more source

Living, Caring, Learning - Thinking outside the box to solve care challenges in a rare blood disorder

The Journal of Haemophilia Practice
A specialist nurse for over 20 years, Sandra reflects on her experience of finding ways to deliver effective care for a young girl with a very rare clotting disorder.
Hibner Sandra
doaj   +1 more source

Significant correlation of angiotensin converting enzyme and glycoprotein IIIa genes polymorphisms with unexplained recurrent pregnancy loss in north of Iran [PDF]

, 2016
Background: Spontaneous abortion is considered as the most complex problem during pregnancy. Thrombophilia is resumed as a cause of recurrent pregnancy loss (RPL). Glycoprotein IIIa (GPIIIa) gene is involved in thrombosis and abortion.
Farazmandfar, T., Fazelnia, S., Hashemi-Soteh, S.M.B.   +2 more
core   +1 more source

Non‐Invasive Multidimensional Capacitive Sensing for In Vivo Traumatic Brain Injury Monitoring

Advanced Materials Technologies, EarlyView.
Single‐electrode, multidimensional capacitive sensors noninvasively assess cerebral autoregulation and compliance for traumatic brain injury monitoring. ABSTRACT Traumatic brain injury (TBI) is a major cause of death and disability, but invasive intracranial pressure (ICP) monitoring is risky, and current non‐invasive methods lack the resolution and ...
Shawn Kim, Yu‐Jen Cheng, Tianyi Li, Nathan White, Xu Wang, Kristyn Ringgold, Lauren Neidig, Younghoon Kwon, Jae‐Hyun Chung   +8 more
wiley   +1 more source

Hydrogel‐Based Functional Materials: Classifications, Properties, and Applications

Advanced Materials Technologies, EarlyView.
Conductive hydrogels have emerged as promising materials for smart wearable devices due to their outstanding flexibility, multifunctionality, and biocompatibility. This review systematically summarizes recent progress in their design strategies, focusing on monomer systems and conductive components, and highlights key multifunctional properties such as
Zeyu Zhang, Zao Cheng, Patrizio Raffa
wiley   +1 more source

The European Hematology Association Roadmap for European Hematology Research: a consensus document [PDF]

, 2016
The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better
Allard, S, Anagnou, N, Andolfo, I, Andrau, J-C, Andre, M, Andre-Schmutz, I, Angelucci, E, Anstee, D, Aurer, I, Avet-Loiseau, H, Aydinok, Y, Bacigalupo, A, Bakchoul, T, Balduini, A, Balduini, C, Barcellini, W, Baruch, D, Baruchel, A, Bayry, J, Bento, C, Bernardi, R, Bianchi, P, Bigas, A, Biondi, A, Bochud, P-Y, Bohonek, M, Bonini, C, Bonnet, D, Borchmann, P, Borregaard, N, Braekkan, S, Brand, A, Brodin, E, Bullinger, L, Buske, C, Butzeck, B, Camaschella, C, Cammenga, J, Campo, E, Cant, A, Cappellini, MD, Carbone, A, Cazzola, M, Cervantes, F, Cesaro, S, Charbord, P, Claas, F, Cohen, H, Coiffier, B, Conard, J, Coppo, P, Cordonnier, C, da Costa, L, Davi, F, De Franceschi, L, de Haan, G, de Haas, F, de Latour, RP, de Montalembert, M, de Wit, TD, Delwel, R, den Boer, M, Dianzani, I, Dimopoulos, M, Doehner, H, Domanovic, D, Donnelly, P, Douay, L, Dreyling, M, Drnovsek, TD, Du, M-Q, Dufour, C, Durand, C, Dzierzak, E, Efremov, D, Eichinger, S, Einsele, H, el Nemer, W, Eleftheriou, A, Elion, J, Emonts, M, Engelhardt, M, Engert, A, Ezine, S, Falkenburg, F, Favier, R, Federico, M, Fenaux, P, Ferreri, A, Fibbe, W, Fitzgibbon, J, Flygare, J, Foa, R, Forrester, L, Galacteros, F, Garagiola, I, Gardiner, C, Garraud, O, Gaulard, P, Geiger, H, Geissler, J, Germing, U, Ghevaert, C, Girelli, D, Godeau, B, Goekbuget, N, Goldschmidt, H, Goodeve, A, Gottgens, B, Graf, T, Graziadei, G, Green, T, Greinacher, A, Gresele, P, Gribben, J, Griesshammer, M, Gruel, Y, Guilhot, F, Gyssens, I, Halter, J, Hansen, J-B, Harrison, C, Harteveld, C, Hellstrom-Lindberg, E, Hermine, O, Higgs, D, Hillmen, P, Hirsch, H, Hochhaus, A, Hoskin, P, Hovinga, JK, Huls, G, Inati, A, Iolascon, A, Jaffredo, T, Johnson, P, Kadir, R, Kattamis, A, Kaveri, S, Kiefel, V, Kleanthous, M, Klump, H, Kouskoff, V, Krause, D, Kuehne, T, Kyrle, P, Lacaud, G, Lacroix-Desmazes, S, Landman-Parker, J, LeGouill, S, Lenz, G, Ljungman, P, Lo Celso, C, Lopez-Guillermo, A, Lopriore, E, Lozano, M, MacIntyre, E, Makris, M, Mannhalter, C, Manuel Soria, J, Maria Ribera, J, Martens, J, Martinez, PA, Maschmeyer, G, Mathas, S, Matzdorff, A, Medvinsky, A, Mendez-Ferrer, S, Menendez, P, Migliaccio, AR, Miharada, K, Mikulska, M, Milsom, M, Minard, V, Montalban, C, Montserrat, E, Morange, P-E, Mountford, J, Muckenthaler, M, Mueller-Tidow, C, Mumford, A, Mummery, C, Nadel, B, Navarro, J-T, Noizat-Pirenne, F, O'Mahony, B, Oldenburg, J, Olsson, M, Oostendorp, R, Ossenkoppele, G, Palumbo, A, Passamonti, F, Patient, R, Pecci, A, Peyvandi, F, Pflumio, F, Philipsen, S, Pierelli, L, Piga, A, Pollard, D, Raaijmakers, M, Radford, J, Rambach, R, Rao, AK, Raslova, H, Rebulla, P, Rees, D, Reitsma, P, Ribrag, V, Rijneveld, A, Rinalducci, S, Risitano, A, Rivella, S, Robak, T, Roberts, I, Rodeghiero, F, Rodrigues, C, Rosendaal, F, Rosenwald, A, Ruf, W, Rule, S, Russo, R, Saglio, G, Salles, G, Sanchez, M, Scharf, RE, Schlenke, P, Schroeder, T, Schuringa, JJ, Scully, M, Semple, J, Sierra, J, So-Osman, C, Socie, G, Staal, F, Stamatopoulos, K, Stanworth, S, Stauder, R, Stegmayr, B, Stilgenbauer, S, Stunnenberg, H, Swinkels, D, Taborda Barata, JP, Taghon, T, Taher, A, Tamary, H, Terpos, E, Thachil, J, Theilgaard-Monch, K, Thein, SL, Tilly, H, Tissot, JD, Touw, I, Toye, A, Trappe, R, Traverse-Glehen, A, Trneny, M, Unal, S, Vainchenker, W, van den Akker, E, van den Berg, A, van den Brink, M, van Geet, C, van Wijk, R, Vannucchi, AM, Vaulont, S, Viprakasit, V, Viscoli, C, Vitolo, U, Vives Corrons, J-L, von Gunten, S, von Lilienfeld-Toal, M, von Lindern, M, Vrielink, H, Wojtowicz, A, Zaaijer, H, Zanella, A, Zeerleder, S, Zieger, B, Zolla, L, Zwaginga, JJ   +280 more
core