Results 141 to 150 of about 1,597,912 (313)

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

Supplemental findings of the 2023 National Blood Collection and Utilization Survey. [PDF]

open access: yesTransfusion
Griffin IS   +7 more
europepmc   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

open access: yesFEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani   +7 more
wiley   +1 more source

Novel Blood Collection Tubes Improve Sample Preservation in a Multicenter Study in Thailand. [PDF]

open access: yesDiagnostics (Basel)
Moonla K   +4 more
europepmc   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Supplementing Inosine to Blood Collection Tubes Adds a Glycolytic Inhibitory Effect. [PDF]

open access: yesJ Diabetes
Kume Y   +6 more
europepmc   +1 more source

Clinical characteristics of the FRESH study participants including the number of days post first observed plasma viraemia for the sample analysed for this study, the stages of early infection when the blood samples were collected, viral load and CD4 T-cell count at the time of sample collection.

open access: green
Bongiwe Ndlovu (6423578)   +16 more
openalex   +1 more source

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