Results 161 to 170 of about 1,597,912 (313)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Evaluating finger-prick blood collection for remote quantification of neurofilament light in neurological diseases. [PDF]

J Neurol
Coleman A, Touzé A, Farag M, Pengo M, Murphy MJ, Hassan Y, Thackeray O, Fayer K, Field S, Nakajima M, Broom EL, Hobbs NZ, Huxford B, Donkor N, Camboe E, Dey KC, Zirra A, Ahmed A, Gameiro Costa AR, Sorrell H, Zampedri L, Lombardi V, Wade C, Mangion S, Fneich B, Heslegrave A, Zetterberg H, Scahill R, Noyce A, Malaspina A, Chataway J, Tabrizi SJ, Byrne LM.   +32 more
europepmc   +1 more source

The effect of lighted toy on reducing pain and fear during blood collection in children between 3 and 6 years: A randomized control trial

, 2023
Mehmet Alperen Turgut, Ayşe Sonay Türkmen   +1 more
openalex   +2 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Intelligent blood collection robot: key technologies, clinical applications, and future challenges. [PDF]

Front Bioeng Biotechnol
Wang Y, Ruan H, Ruan Y, Li Q, Wang C, Fang Z.   +5 more
europepmc   +1 more source

Embossed Paper Platform for Whole Blood Collection, Room Temperature Storage, and Direct Analysis by Pinhole Paper Spray Mass Spectrometry

, 2022
Benjamin S. Frey, Derik R. Heiss, Abraham K. Badu‐Tawiah   +2 more
openalex   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Current status of research on hematological testing of blood collected from hemodialysis filtration tubes in patients treated with CRRT

Huli yanjiu, 2023
YI Jinyan, YANG Li, ZHONG Bohua, YI Zihui, XU Wei, LIN Haicheng   +5 more
doaj  

Remote Blood Collection for Telomere Length Measurement: Assessing the Impact of Sample Characteristics and Handling on DNA Quality and Assay Outcomes. [PDF]

Am J Hum Biol
Conklin QA, Smith DL, Dai G, King BG, Saron CD, Lin J.   +5 more
europepmc   +1 more source

Automated collection of double red blood cell units with a variable‐volume separation chamber [PDF]

, 2007
James P. AuBuchon, Larry J. Dumont, Louise Herschel, J Roger, R. Beddard, Harry L. Taylor, Pamela Whitley, Sherrie Sawyer, Sharon Graminske, Karen Martinson, Ross Dora, Sybil Heldke, John W. Adamson, Leslie Rose   +13 more
openalex   +1 more source