Results 201 to 210 of about 11,652,656 (310)

Is it possible to use complete blood collection based systemic inflammatory indices as potential biomarkers for chronic spontaneous urticaria. [PDF]

Front Immunol
Li B, Peng L, Li R, Shi M, Li Y, Sun C, Zhang Z, Xue J, Zhao Y.   +8 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Supplemental findings of the 2023 National Blood Collection and Utilization Survey. [PDF]

Transfusion
Griffin IS, Kracalik I, McDavid K, Bradley T, Ortiz JC, Berger JJ, Basavaraju SV, Lien R.   +7 more
europepmc   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

Comparing capillary blood collection technologies: assessing patient experience, device performance, & clinical accuracy. [PDF]

Bioanalysis
Collier BB, Brandon WC, Chappell MR, Iacovetti G, Tokunaga N, Schaff UY, Sommer GJ, Grant RP.   +7 more
europepmc   +1 more source

In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans

FEBS Open Bio, EarlyView.
In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller, Jana Bleher, Birgit Weinberger, Lourdes Rocamora‐Reverte   +3 more
wiley   +1 more source

Situating and repositioning disability within the blood donation context: Insights from 12 blood collection agencies. [PDF]

Transfusion
Philip AA, Thorpe R, Masser BM.
europepmc   +1 more source

Ultrafast visual detection of Streptococcus suis via HtpsC‐targeted LAMP–CRISPR–Cas12a coupled with lateral flow immunochromatography

FEBS Open Bio, EarlyView.
A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li, Miao Xin, Xiao‐wen Cui, Shi‐yin Yu, Fei Meng, Min Cao, Xiao‐hui Xiong, Yi‐chen Lu   +7 more
wiley   +1 more source

Unexpected scarring following use of capillary self-blood collection device: A case report and discussion of device design. [PDF]

J Vasc Access
Müller F, Hafke A, Schanz J, Hummers E, Brockmeyer P, Kuhnke L, Schröder D.   +6 more
europepmc   +1 more source