Results 211 to 220 of about 7,178,224 (293)

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

open access: yesAdvanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren   +6 more
wiley   +1 more source

A Coaxial Bioprinted Hydrogel With Semipermeable Sheath and Pro‐Chondrogenic Core for Articular Cartilage Repair

open access: yesAdvanced Materials, EarlyView.
A sheath‐core biomimetic hydrogel is engineered with a compartmentalized yet integrated architecture for synergistic multifunctionality. Its stiff, semipermeable sheath mimics the ECM's load‐bearing and protective roles, encapsulating a soft core that provides a pro‐chondrogenic microenvironment similar to the PCM.
Zheyuan Shi   +9 more
wiley   +1 more source

An Engineered Thio‐Amino Polymer Achieves Potent, Safe, and Broad Cell Type Delivery in the Lung Mapped by Spatial Transcriptomics

open access: yesAdvanced Materials, EarlyView.
Synthesis and screening of a polymer library produced a versatile and inhalable mRNA vehicle for the lungs (P81). Compared to a published LNP, P81 provides increased delivery efficacy, achieving widespread expression in broad cell types, with no toxicity.
Pramodkumar EK   +36 more
wiley   +1 more source

Life‐Like Ferrous Oxide Microspheres from Kombucha

open access: yesAdvanced Materials Interfaces, EarlyView.
Kombucha bacterial cellulose, sodium alginate, and ferrous nitrate self‐assemble into membrane‐enclosed iron oxide microspheres. These microspheres bud daughter vesicles, sustain 24‐h electrochemical oscillations, and filter theta‐band signals.
Panagiotis Mougkogiannis   +2 more
wiley   +1 more source

Effect of red blood cell processing on hemoglobin increment in oncology patients. [PDF]

open access: yesHematol Transfus Cell Ther
Shekhar Sameer M   +6 more
europepmc   +1 more source

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