Results 101 to 110 of about 6,419,415 (265)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

WHO recommendations for the use of blood components.

open access: yes, 2019
WHO recommendations for the use of blood components.
Fábio Juliano Negrão (625690)   +4 more
core   +1 more source

Transfusion-related acute lung injury – afrequently undiagnosed reaction following transfusion ofblood components [PDF]

open access: yes, 2015
Transfusion-related acute lung injury is the leading cause of mortality following transfusion of blood components. Its characteristic feature is acute hypoxaemia during or 6 hours after transfusion.
Łata, Anna   +3 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The proposal to discontinue blood testing at the Munster Centre of the Irish Blood Transfusion Service Board (BTSB) - assessment by a representative regional group

open access: yes, 1998
The role of the Irish Blood Transfusion Service is crucial to the operation of our health care system. In its 1965 Establishment Order, the key functions of the BTSB are described, inter alia, as follows (a) to take over the property {including chosen ...
Irish Blood Transfusion Service (IBTS)
core  

Relationship of Lead Exposure with Workers\' Blood Pressure and Blood Components: A Case Study

open access: yesArchives of Occupational Health, 2020
Background: Lead is one of the most widely used metals in the industries and is the amplest metal element on the Earth’s crust. This metal disrupts the physiological processes of the body due to its accumulation in various tissues.
Salman Torabi Goodarzi   +5 more
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

BLOOD PRODUCT PRESCRIPTION INFORMED CONSENT

open access: yes, 2015
The prescription of blood and blood components is the responsibility of a doctor or midwife / nurse practitioner licensed to prescribe blood components).
Blood Transfusion   +4 more
core  

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