Results 161 to 170 of about 1,235,772 (263)

Performance evaluation of hematology analyzer XN-10 (Blood Bank mode) and its comparison with flow-cytometer for quality control (QC) of leukodepleted blood components: Pilot Study. [PDF]

Asian J Transfus Sci
Tiwari AK, Chauhan R, Kashyap S, Rawat GS, Kahlon S, Jadhav V, Sethi M.   +6 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Blood donation practices, processing and utilisation of blood components in government tertiary hospitals in Nigeria: a multicentre cooperative study. [PDF]

Int Health
Umar G, Abdulqadir I, Ugwu N, Adeyemo T, Yau N, Hassan A, Olaniyi J, Musa A, Abubakar S, Ndakotsu M, James J, Uche C, Musa A, Ukoma C, Nwogoh B, David E, Ugwu A, Nwankwo C, Omokanye O, Abba A, Owojuyigbe T, Isyaku M, Obi E, Jatau E, Ekwere T, Oladosu-Olayiwola R, Isah H, Diggi S, Nwannadi A, Yuguda S, Iheanacho O, Tikau H, Adeleke I, Ekanem M, Madu A, Ikusemoro A, Chukwu C, Galadanci A, Bassey O, Otu T, Agwu O, Osho P, Gwarzo A, Hassan S, Majeed A, Umar A, Abubakar H, Gimba M, Ugbor M, Ali A, Ajuba C.   +50 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Growth and Distribution of Bacteria in Contaminated Whole Blood and Derived Blood Components. [PDF]

Transfus Med Hemother
Gravemann U, Handke W, Schulze TJ, Seltsam A.   +3 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Venom from <i>Loxosceles</i> Spiders Collected in Southeastern and Northeastern Brazilian Regions Cause Hemotoxic Effects on Human Blood Components. [PDF]

Toxins (Basel)
Silva-Magalhães R, Gomes Dos Santos AM, Silva-Araújo AL, Peres-Damásio PL, Gonçalves de Alvarenga V, Souza de Oliveira L, Sanchez EF, Chávez-Olórtegui C, Varela LSDRN, Paiva ALB, Guerra-Duarte C.   +10 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Influence of Blood Components on Neuroinflammation, Blood-Brain Barrier Breakdown, and Functional Damage After Acute Subdural Hematoma in Rats. [PDF]

Neurotrauma Rep
Jussen D, Saeed S, Jablonski T, Krenzlin H, Lucia K, Kraemer T, Kempski O, Czabanka M, Ringel F, Alessandri B.   +9 more
europepmc   +1 more source