Results 161 to 170 of about 10,888,759 (408)

Maintaining osteoclastogenesis following allogeneic hematopoietic stem cell transplantation for osteopetrosis: evidence from in vitro testing

Haematologica, 2022
Süreyya Savaşan, Manisha Gadgeel, Cathryn Freeman, Omar Moussa   +3 more
doaj   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

PB2006: CHARACTERISTICS AND OUTCOMES OF PATIENTS WITH PLASMA CELL LEUKEMIA (PCL): A SINGLE-CENTER STUDY FROM TUNISIA

HemaSphere, 2022
Y. Fakhfakh, F. Kammoun, O. Kassar, F. Kallel, M. Chaari, N. Louati, L. Torjeman, M. Charfi, I. Frikha, I. Ben Amor, L. Khalifa, M. Medhafar, S. Hadiji, H. Elleuch, H. Mnif, T. Ben Othman, M. Elloumi   +16 more
doaj   +1 more source

Pulmonary consequences of experimentally induced stroke: differences between global and focal cerebral ischemia

Frontiers in Physiology
IntroductionCerebral ischemia leads to multiple organ dysfunctions, with the lungs among the most severely affected. Although adverse pulmonary consequences contribute significantly to reduced life expectancy after stroke, the impact of global or focal ...
Petra Somogyi, Petra Somogyi, Petra Somogyi, Ibolya Tóth, Bence Ballók, Zaid Hammad, Ramez A. Hussein, Fruzsina Kun-Szabó, József Tolnai, Judit Danis, Szilvia Kecskés, Szilvia Kecskés, Gergely H. Fodor, Eszter Farkas, Eszter Farkas, Ferenc Peták   +15 more
doaj   +1 more source

THE CEREBRAL BLOOD FLOW IN MALE SUBJECTS AS MEASURED BY THE NITROUS OXIDE TECHNIQUE. NORMAL VALUES FOR BLOOD FLOW, OXYGEN UTILIZATION, GLUCOSE UTILIZATION, AND PERIPHERAL RESISTANCE, WITH OBSERVATIONS ON THE EFFECT OF TILTING AND ANXIETY 1 [PDF]

, 1949
Peritz Scheinberg, Eugene A. Stead
openalex   +1 more source

Glomerular blood flow

Kidney International, 1990
Karlhans Endlich, Wiegman Dl, Michael Steinhausen   +2 more
openaire   +3 more sources

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

An Adaptation of the Nitrous Oxide Method to the Study of the Cerebral Circulation in Children; Normal Values for Cerebral Blood Flow and Cerebral Metabolic Rate in Childhood1 [PDF]

, 1957
Charles Kennedy, Louis Sokoloff
openalex   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Methods for Determining Blood Flow Through Intact Vessels of Experimental Animals Under Conditions of Gravitational Stress and in Extra-terrestrial Space Capsules Final Report, 1 Nov. 1960 - 31 Dec. 1964 [PDF]

Electromagnetic blood flow meter to determine blood flow through intact vessels of test animals in gravitational stress and in extraterrestrial space ...
Sciorra, A. F., Shaw, R. F.
core   +1 more source