Results 81 to 90 of about 6,939,165 (291)
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Juxtamedullary blood flow pathway
Вестник урологии, 2019 Golubev V.Z. created a scientific basis for the study of microangioarchitecture of the kidneys. The principles outlined in his thesis mediated appearance of studies investigating juxtamedullary blood flow and renal blood circulation in normal and ...
O. A. Kaplunova
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Cerebral blood flow and behavioural effects of caffeine in habitual and non-habitual consumers of caffeine: A near infrared spectroscopy study [PDF]
, 2011 Caffeine has been shown to modulate cerebral blood flow, with little evidence of tolerance to these effects following habitual use. However, previous studies have focused on caffeine levels much higher than those found in dietary servings and have ...
Haskell, Crystal +3 more
core +1 more source
Indian Journal of Ophthalmology, 2017 Studies have shown that vascular impairment plays an important role in the etiology and pathogenesis of various ocular diseases including glaucoma, age-related macular degeneration, diabetic retinopathy, and retinal venous occlusive disease.
Jyotsna Maram +2 more
doaj +1 more source
British Journal of Ophthalmology, 2006 Glaucoma: a vascular dysregulation Increased cupping of the optic nerve head, a result of progressive loss of the retinal nerve fibres and remodelling of the supporting connective tissue in and around the lamina cribrosa, characterises glaucomatous optic neuropathy. Although reducing intraocular pressure represents a relevant approach in the treatment
openaire +2 more sources
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
The role of large arteries in controlling blood flow to the hand during severe local cooling. [PDF]
, 1995 PhDCold vasodilatation describes the increase in blood flow that follows initial vaso constriction when an extremity is exposed to an environment colder than 12'C. It appears to be due mainly to cold paralysis of local resistance vessels.
Whelan, Laurence John
core +2 more sources
NeurotherapeuticsAcute ischemic stroke is a major cause of death and disability, yet many patients cannot engage in early rehabilitation due to severe motor deficits. Resulting immobility accelerates muscle atrophy and systemic inflammation, highlighting muscle–brain ...
Anna Törteli +10 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source