Results 91 to 100 of about 5,413,902 (242)

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Blood Flow Restriction Training in Postoperative Musculoskeletal Rehabilitation

Journal of Education, Health and Sport
Background: Blood flow restriction (BFR) training applies partial vascular occlusion during low-load exercise, offering a clinically compelling adjunct in postoperative rehabilitation.
Bartosz Rodziewicz, Mateusz Fidut, Mikołaj Kacperski   +2 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Effects of blood flow restriction on motoneurons synchronization

Frontiers in Neural Circuits
Blood flow restriction (BFR) is a peripheral intervention that induces transient and reversible physiological perturbations. While this intervention offers a unique model to explore neuromuscular responses in multiple contexts, its impact on neural input
Mansour Taleshi, Franziska Bubeck, Franziska Bubeck, Leonardo Gizzi, Ivan Vujaklija   +4 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

The Discrepancy Between External and Internal Load/Intensity during Blood Flow Restriction Exercise: Understanding Blood Flow Restriction Pressure as Modulating Factor

Sports Medicine - Open
Physical exercise induces acute psychophysiological responses leading to chronic adaptations when the exercise stimulus is applied repeatedly, at sufficient time periods, and with appropriate magnitude.
Robert Bielitzki, Martin Behrens, Tom Behrendt, Alexander Franz, Christoph Centner, Luke Hughes, Stephen D. Patterson, Johnny Owens, Michael Behringer, Lutz Schega   +9 more
doaj   +1 more source

Tourniquet cuff pressure during blood flow restriction exercise

Frontiers in Sports and Active Living
BackgroundThe present study examined how well different blood flow restriction (BFR) devices deliver the prescribed tourniquet cuff pressure.MethodsFifteen participants completed four BFR exercise sessions, each with a different BFR device [Delfi ...
Patrick Swain, James McEwen, James McEwen, Tom Lai, Luke Hughes   +4 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Can Blood Flow Restriction Be the Key to Reducing Quadriceps Weakness in the Early and Mid-Phases After Anterior Cruciate Ligament Reconstruction with a Hamstring Graft? A Systematic Review of Randomized Controlled Trials

Diagnostics
Background: Injury to the anterior cruciate ligament is one of the most common knee injuries. Following anterior cruciate ligament reconstruction, strength deficits and reduced quadriceps and hamstring muscle mass are common.
Ayrton Moiroux--Sahraoui, Jean Mazeas, Marine Blossier, Maurice Douryang, Georges Kakavas, Timothy E. Hewett, Florian Forelli   +6 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source