Results 61 to 70 of about 5,413,902 (242)
Human red blood cells at work: identification and visualization of erythrocytic eNOS activity in health and disease [PDF]
, 2012 A nitric oxide synthase (NOS)-like activity has been demonstrated in human red blood cells (RBCs), but doubts about its functional significance, isoform identity and disease relevance remain.
Rodriguez-Mateos, Ana; id_orcid +33 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Renal pericytes: regulators of medullary blood flow [PDF]
, 2012 Regulation of medullary blood flow (MBF) is essential in maintaining normal kidney function. Blood flow to the medulla is supplied by the descending vasa recta (DVR), which arise from the efferent arterioles of juxtamedullary glomeruli.
Peppiatt-Wildman, Claire M. +10 more
core +1 more source
Huli yanjiu, 2023 This study described the concept，mechanism and application parameters of blood flow restriction exercise，and reviewed the application status quo of blood flow restriction exercise in exercise intervention of the elderly，in order to provide reference for ...
ZHANG Jiajia, ZHOU Qian, ZHANG Weihong
doaj
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Medical Laboratory Journal, 2020 Background and Objectives: It has been shown that low intensity physical activity rarely increases bone density or renewal. Therefore, the purpose of this study was to investigate effects of four weeks of plyometric training with and without vascular ...
Fatemeh Fakhri +3 more
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
BMC Sports Science, Medicine and RehabilitationBackground Blood flow restriction training (BFRT) has emerged as a promising way to enhance strength and build muscle with low-load exercises. This study was aimed to evaluate the effects of upper limb BFRT on shoulder strength.
Hediyeh Hamedi +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
The Effect of Low-intensity TRX Suspension Training with Blood Flow Restriction on Serum Levels of Angiogenesis Factors VEGF, HIF-1, and Body Composition in Active Female [PDF]
تحقیقات سلامت در جامعهIntroduction and purpose: Resistance training with blood flow restriction increases the recruitment of fast-twitch fibers in hypoxia conditions. It also boosts the synthesis of muscle protein with anabolic hormone indices.
Parisa Basiri +2 more
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