Results 141 to 150 of about 1,011,739 (356)

Delivery of Islatravir via High Drug‐Load, Long‐acting Microarray Patches for the Prevention or Treatment of Human Immunodeficiency Virus

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Islatravir‐loaded dissolving microarray patches (MAPs) provide a minimally invasive, long‐acting solution for HIV‐1 prevention and treatment. In rats, sustained islatravir delivery lasts up to three months, while in minipigs, efficacious plasma levels are detected for six days.
Qonita Kurnia Anjani   +11 more
wiley   +1 more source

Reservoir‐Type Subcutaneous Implantable Devices Containing Porous Rate Controlling Membranes for Sustained Delivery of Risperidone

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a novel implantable drug delivery systemwith a biodegradable poly(caprolactone) membrane and compressed drug core forsustained release. These implantable devices deliver risperidone in vitro for 170 days and in vivo for 49 days in rats, showing promise for chronic conditions like schizophrenia.
Linlin Li   +9 more
wiley   +1 more source

Relationship between umbilical and fetal cerebral blood flow velocity waveforms and umbilical venous blood gases [PDF]

open access: bronze, 1992
Philippe Bonnin   +5 more
openalex   +1 more source

Dexamethasone Delivery via Amphiphilic, Low‐swelling Hydrogels Treats Postoperative Inflammation in Cervical Spine Applications

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
DexaPatch, an implantable, low‐swelling amphiphilic hydrogel system containing dexamethasone‐PLGA microparticles, is developed and characterized for sustained local steroid release to reduce postoperative inflammation in tight surgical spaces. DexaPatch significantly reduces postoperative edema and fibrosis in a rabbit model of anterior spinal surgery,
Stephen W. Linderman   +6 more
wiley   +1 more source

A Deep Learning Framework for the Detection of Abnormality in Cerebral Blood Flow Velocity Using Transcranial Doppler Ultrasound. [PDF]

open access: yesDiagnostics (Basel), 2023
Nisha NN   +8 more
europepmc   +1 more source

Implementing BMP‐7 Chemically Modified RNA for Bone Regeneration with 3D Printable Hyaluronic Acid‐Collagen Granular Gels

open access: yesAdvanced Healthcare Materials, EarlyView.
This study developed 3D‐printable THA‐Col microgels for delivering BMP‐7 cmRNA. The key result is that hMSCs transfected on the biomaterials showed BMP‐7 secretion levels comparable to pre‐transfected hMSCs, therefore introducing a cmRNA‐activated matrix to promote bone healing.
Daphne van der Heide   +7 more
wiley   +1 more source

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