Results 191 to 200 of about 1,364,033 (418)

Development of Itaconate Polymers Microparticles for Intracellular Regulation of Pro‐Inflammatory Macrophage Activation

open access: yesAdvanced Healthcare Materials, EarlyView.
This study develops itaconate‐based polymer microparticles (IA‐MPs) for macrophage‐targeted intracellular delivery, overcoming the limitations of traditional itaconate administration. IA‐MPs achieve controlled release through phagocytosis, reducing pro‐inflammatory cytokine expression and reprogramming macrophage metabolism toward glycolysis.
Kaitlyn E. Woodworth   +10 more
wiley   +1 more source

Mathematical Modelling of Blood Flow through Catheterized Artery under the Influence of Body Acceleration with Slip Velocity [PDF]

open access: yes, 2013
The flow of blood through stenosed catheterized artery with the effect of external body acceleration has been considered. The pulsatile flow behaviour of blood in an artery subjected to the pulsatile pressure gradient and slip velocity has been studied ...
Geeta, Sapna, Siddiqui, S. U.
core   +1 more source

Advanced Materials for Biological Field‐Effect Transistors (Bio‐FETs) in Precision Healthcare and Biosensing

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores how advanced materials enhance Bio‐FETs for precision healthcare and biosensing. It covers their working principles, surface functionalization, and ultra‐sensitive detection capabilities. The integration of flexible designs, AI, and IoT for real‐time monitoring is discussed, along with challenges like material reproducibility and ...
Minal Pandey   +5 more
wiley   +1 more source

Vessel Sampling and Blood Flow Velocity Distribution With Vessel Diameter for Characterizing the Human Bulbar Conjunctival Microvasculature

open access: yesEye & contact lens, 2016
Liang Wang   +8 more
semanticscholar   +1 more source

Biohybrid Vascular Graft Made of Textile‐Reinforced Elastin‐Like Recombinamers and Its Preservation via Drying Processes

open access: yesAdvanced Healthcare Materials, EarlyView.
Clinical translation of biohybrid medical implants requires the previous implementation of drying schemes that can facilitate their sterilization and storage. This study addresses that critical aspect and elucidates the impact of drying on biohybrid vascular grafts, highlighting the need for implant‐specific drying strategies to ensure safety ...
Dominic Pascal Andre   +5 more
wiley   +1 more source

Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response

open access: yesAdvanced Healthcare Materials, EarlyView.
In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim   +11 more
wiley   +1 more source

Influence of Hypoxia on a Biomaterial Model of the Bone Marrow Perivascular Niche

open access: yesAdvanced Healthcare Materials, EarlyView.
Hypoxia is a key factor in bone marrow physiology and hematopoietic stem cell behavior. Lower oxygen tension influences the secretion of vasculature‐derived hematopoietic regulatory factors and alters hematopoietic cell behavior in a conditioned medium hydrogel model of bone marrow. Cyclosporin A is used to mitigate normoxic stress during hematopoietic
Gunnar B. Thompson   +3 more
wiley   +1 more source

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