The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik+3 more
wiley +1 more source
Macular hemodynamic responses to short-term acute exercise in young healthy adults [PDF]
We investigated the effects of vigorous exercise on blood flow in the macular vasculature. The velocity and density of entoptically viewed leukocytes in the paramacular retinal capillaries were measured with an Oculix BFS-2000 blue field simulator in 18 ...
Forcier, Pierre+2 more
core +1 more source
Hemodynamical Behavior Analysis of Anemic, Diabetic, and Healthy Blood Flow in the Carotid Artery [PDF]
The influence of blood rheology on hemodynamic parameters is investigated using Computational Fluid Dynamics on blood flow through the human carotid artery. We performed three-dimensional modeling and simulation to study blood flow through the carotid artery, which is divided into internal and exterior parts with a decreased radius.
arxiv +1 more source
Comparative Mathematical Study of Blood Flow Through Stenotic and Aneurysmatic Artery with the Presence and Absence of Blood clots [PDF]
Numerical predictions of blood flow and hemodynamic properties through a stenotic and aneurysmal rigid artery are studied in the presence of blood clot at constricted area. Finite element method has been used to solve the steady partial differential equations of continuity, momentum, Oldroyd-B and bioheat transport in two dimensional cartesian ...
arxiv
Cerebral autoregulation in patients with acute lacunar infarction: a reliable predictor of outcome
Abstract Objective To further investigate the association between dynamic cerebral autoregulation (dCA) and the outcomes in patients with acute lacunar infarction. Methods Patients were prospectively and consecutively enrolled at The First Hospital of Jilin University between 2016 and 2023. dCA was monitored at 1–3 and 7–10 days after the stroke.
Xiang‐Kun Si+7 more
wiley +1 more source
Segmentation of TCD Cerebral Blood Flow Velocity Recordings [PDF]
A binary beat-by-beat classification algorithm for cerebral blood flow velocity (CBFV) recordings based on amplitude, spectral and morphological features is presented. The classification difference between 15 manually and algorithmically annotated CBFV records is around 5%.
arxiv
Multiscale Parareal Algorithm for Long-Time Mesoscopic Simulations of Microvascular Blood Flow in Zebrafish [PDF]
Various biological processes such as transport of oxygen and nutrients, thrombus formation, vascular angiogenesis and remodeling are related to cellular/subcellular level biological processes, where mesoscopic simulations resolving detailed cell dynamics provide a key to understanding and identifying the cellular basis of disease.
arxiv
Immediate Effect of Physical Exercise on Blood Flow Velocity in Radial Artery in Young Adults [PDF]
Purpose: Quantify changes in blood flow velocity in radial artery after local dynamic exercise and compare these results between a group of women and men. Acquire data of normal resting blood flow in radial artery. Methods: We examined 42 healthy young
Jůza, Tomáš, Vlk, Daniel
core +1 more source
BackgroundSleep disordered breathing in children is associated with increased blood flow velocity and sympathetic overactivity. Sympathetic overactivity results in peripheral vasoconstriction and reduced systemic vascular compliance, which increases ...
Anna Kontos+12 more
doaj +1 more source
Amygdala Neurodegeneration: A Key Driver of Visual Dysfunction in Parkinson's Disease
ABSTRACT Objective Visual disability in Parkinson's disease (PD) is not fully explained by retinal neurodegeneration. We aimed to delineate the brain substrate of visual dysfunction in PD and its association with retinal thickness. Methods Forty‐two PD patients and 29 controls underwent 3‐Tesla MRI, retinal spectral‐domain optical coherence tomography,
Asier Erramuzpe+15 more
wiley +1 more source