Results 71 to 80 of about 1,758,208 (306)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

ON THE BLOOD GLUCOSE DYNAMICS MODELLING

Mathematical Modelling and Analysis, 1998
Mathematical model of the glucose regulation is proposed and discussed. It is based only on the data, which are available in outpatient clinics. This model enables to predict the state of the patients health and to identificate important parameters of patients organism, which are urgent in diabetology.
openaire   +5 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

PENGARUH KADAR GLUKOSA DARAH SEWAKTU TERHADAP KELUARAN NEUROLOGIK PADA PENDERITA STROKE ISKEMIK FASE AKUT NONDIABETIK [PDF]

, 2011
Background : An increasing of blood glucose levels is presumed to aggravate the neurological outcome of ischemic stroke patients. The research about association between increased blood glucose levels on nondiabetic patients with ischemic stroke and the ...
Napitupulu, Edward Yando
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

The relationships between blood pressure, blood glucose, and bone mineral density in postmenopausal Turkish women

Therapeutics and Clinical Risk Management, 2015
Huseyin Altug Cakmak,1 Burcu Dincgez Cakmak,2 Ayse Ender Yumru,3 Serkan Aslan,4 Asim Enhos,1 Ali Kemal Kalkan,4 Ebru Inci Coskun,5 Abdullah Serdar Acikgoz,6 Suat Karatas3 1Department of Cardiology, Mustafakemalpasa Government Hospital, Bursa ...
Cakmak HA, Cakmak BD, Yumru AE, Aslan S, Enhos A, Kalkan AK, Inci Coskun E, Acikgoz AS, Karatas S   +8 more
doaj  

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Construction of blood glucose management guidance flow chart for hemodialysis patients based on best evidence

Huli yanjiu, 2023
ObjectiveTo evaluate and summarize the relevant evidence of blood glucose management in hemodialysis patients，and construct a blood glucose management guidance flow chart for hemodialysis patients based on the best evidence to provide a basis for ...
LU Honghua, XIAO Liping, LIU Yanyan
doaj  

A 21-day Daniel fast with or without krill oil supplementation improves anthropometric parameters and the cardiometabolic profile in men and women

Nutrition & Metabolism, 2012
Background The Daniel Fast is a vegan diet that prohibits the consumption of animal products, refined foods, white flour, preservatives, additives, sweeteners, flavorings, caffeine, and alcohol.
Trepanowski John F, Kabir Mohammad M, Alleman Rick J, Bloomer Richard J   +3 more
doaj   +1 more source