Results 71 to 80 of about 1,192,396 (309)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Glucose effects on long-term memory performance : duration and domain specificity. [PDF]

, 2010
Rational; Previous research has suggested that long term- verbal declarative memory is particularly sensitive to enhancement by glucose loading, however investigation of glucose effects on certain memory domains has hitherto been neglected.
Sünram-Lea, Sandra I., Sandra I. Sünram-Lea, Finnegan, Yvonne, Hu, Henglong, Scholey, Andrew B., Yvonne Finnegan, Owen, Laura, Lauren Owen, Henglong Hu, Andrew B. Scholey   +9 more
core   +1 more source

Effects of Sampling and Storage Method on Chicken Blood Glucose Measurement

The Journal of Poultry Science, 2020
Glucose is a major circulating carbohydrate in birds and its level in the blood is often used as a biometric indicator in clinical diagnosis and various studies.
Takeshi Kawasaki, Tomohito Iwasaki, Itsuki Ohya, Yasuhiro Hasegawa, Mitsuo Noguchi, Takafumi Watanabe   +5 more
doaj   +1 more source

ON THE BLOOD GLUCOSE DYNAMICS MODELLING

Mathematical Modelling and Analysis, 1998
Mathematical model of the glucose regulation is proposed and discussed. It is based only on the data, which are available in outpatient clinics. This model enables to predict the state of the patients health and to identificate important parameters of patients organism, which are urgent in diabetology.
openaire   +5 more sources

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Niosomes and polymeric chitosan based vesicles bearing transferrin and glucose ligands for drug targeting [PDF]

, 2000
PURPOSE: To prepare polymeric vesicles and niosomes bearing glucose or transferrin ligands for drug targeting. METHODS: A glucose-palmitoyl glycol chitosan (PGC) conjugate was synthesised and glucose-PGC polymeric vesicles prepared by sonication of ...
Dufès, Christine, Uchegbu, I.F., Couet, W., Tetley, L., Gray, A.I., Watson, D.G., Olivier, J.C., Schätzlein, A.G.   +7 more
core   +1 more source

Construction of blood glucose management guidance flow chart for hemodialysis patients based on best evidence

Huli yanjiu, 2023
ObjectiveTo evaluate and summarize the relevant evidence of blood glucose management in hemodialysis patients，and construct a blood glucose management guidance flow chart for hemodialysis patients based on the best evidence to provide a basis for ...
LU Honghua, XIAO Liping, LIU Yanyan
doaj