Results 141 to 150 of about 8,820,476 (247)

Dose-response relationship between gestational blood glucose levels and risk of pre-eclampsia in singleton pregnancies: A retrospective multicenter study. [PDF]

Chin Med J (Engl)
Ma S, Gu T, Shi H, Wei Y, Wang X.
europepmc   +1 more source

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source

Gender disparities in random blood glucose levels among Pakistani adults with type 2 diabetes: a cross-sectional analysis. [PDF]

Sci Rep
Khan R, Rashid S, Khan S, Pari B.
europepmc   +1 more source

Thymosin Alpha‐1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis

Advanced Science, EarlyView.
In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang, Shisi Wang, Liubin Zhang, Mengyan Hu, Xiaotao Su, Yuxin Liu, Qin Qin, Haotong Yi, Liling Yuan, Wei Cai, Lei Wei, Zhengqi Lu   +11 more
wiley   +1 more source

Impact of chronic khat chewing on liver function tests and fasting blood glucose levels among adult male khat chewers. [PDF]

Sci Rep
Abreham A, Getaneh A, Dedefo G, Alem M, Bayih A, Tsegaye M, Gashaw B, Gemechu G, Abay Y, Negesso AE, Wolde M, Kinde S.   +11 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Blood Glucose Levels and Stroke Severity in Patients with Acute Small Subcortical Infarct. [PDF]

Brain Sci
Mombelli S, Rinaldi C, Morotti A, Forlivesi S, Bassi C, Zedde M, Pascarella R, Reale G, Caliandro P, Zauli A, Mazzacane F, Del Bello B, Zini A, Arba F.   +13 more
europepmc   +1 more source

Blood pressure as it relates to physique, blood glucose, and serum cholesterol, United States, 1960-1962 [PDF]

A tabular presentation of the data and a multiple regression analysis of blood pressure on five somatic measurements and their derivatives, and on blood glucose and serum cholesterol by age, sex, and race.[by Charles du V. Florey and Roy M.

core  

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

Advanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen, Yan Yang, Haihan Gao, Yan Liu, Xinyue Wang, Linghao Song, Ruohong Li, Ao Miao, Jie Xu, Zhennan Zhao, Dan Li, Shenjie Peng, Linzhao Li, Min Zhang, Yonghang Liu, Liren Wang, Tianhui Chen, Yongxiang Jiang   +17 more
wiley   +1 more source

Effects of blood pressure and blood glucose levels on foveal avascular zone area. [PDF]

BMC Ophthalmol
Ma JB, Qin MZ, Cao K, Zhang YP, Guo CX.
europepmc   +1 more source