Results 61 to 70 of about 3,071,300 (338)

Effect of yoga on blood glucose levels in patients with type 2 diabetes mellitus.

Journal of clinical and diagnostic research : JCDR, 2015
INTRODUCTION In view of people embracing sedentary life style, and the effectiveness of treatment becoming less, the role of regular exercise especially 'yoga' seems to be a beneficial and economical adjuvant in the management of the Type 2 diabetes ...
S. Chimkode, Sendil D Kumaran, V. Kanhere, Ragunatha Shivanna   +3 more
semanticscholar   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Poundfit exercise and cardiometabolic health in women: a quasi-experimental study

Medisains
Background: Poundfit is a rhythmic, music-driven aerobic exercise that integrates cardiovascular movement and strength-based activities. Despite its growing popularity, evidence regarding its effects on cardiometabolic parameters in healthy adults ...
Adi Sucipto, Irianti Fitri Rahmadani, Yuni Afriani, Siska Puspita Sari, Dhelsiana Rambu Desi Boru, Dinda Rambu Nabila, Desty Ervira Puspaningtyas   +6 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

The effect combination of black seed (nigella sativa) and glibenclamide on blood glucose levels

Jurnal Kedokteran Diponegoro
Background: Diabetes Mellitus was considered one of the most alarming pandemics of the twenty-first century before the advent of the COVID-19 pandemic. Glibenclamide (glyburide) is an anti-DM drug of the sulfonylurea class.
Erika Martining Wardani, Riezky Faisal Nugroho   +1 more
doaj   +1 more source

The Antidiabetic Activity of Curry Leaves “Murraya Koenigii” on the Glucose Levels, Kidneys, and Islets of Langerhans of Rats with Streptozotocin Induced Diabetes [PDF]

, 2017
Background: The aims of this study were to explore the antihyperglycemic effect of curry leaves, Murraya koenigii "MK" aqueous extract, and to examine its possible protective effects on the islets of Langerhans and kidneys of streptozotocin (STZ ...
Al-Ani, I. M. (Imad), Alazzawi, K. S. (Khalid), Santosa, R. I. (Rahajoe), Saxena, A. K. (Anil), Yankuzo, M. H. (Muhammad)   +4 more
core  

High-normal blood glucose levels may be associated with decreased spatial perception in young healthy adults. [PDF]

, 2018
The negative effects of high normal glucose on cognitive function were previously reported in euglycemic individuals of middle age and the elderly population.
A Boehmer, A Kemeny, A Simmons, AB Scholey, Abdulla Faisal Alshaiji, Abdulrahman Ahmed Qareeballa, AC Guyton, C Lopez, C Messier, FW Akin, G Mazibrada, H Nyborg, H Nyborg, J Bagust, J Bagust, J Bagust, J Bagust, J Cohen, J Waterhouse, JE Sprague, Jeff Bagust, JS Durmer, K Murray, K Noriaki, L Kerti, LC Perlmuter, M Reivich, ME Mortby, MMK Hijazi, Mohamed Wael Mohamed, N Cherbuin, PK Crane, R Abdul Razzak, R Nakashima, R Roky, R Roky, RAA Vingerhoets, Rima Abdul Razzak, RJ McCrimmon, RT Donohoe, S Docherty, S Fitzgerald, S Fitzgerald, Sharon Docherty, Stephen L. Atkin, T Reilly, T Romeas   +46 more
core   +2 more sources