Results 61 to 70 of about 1,375,669 (297)

Can saliva offer an advantage in monitoring of diabetes mellitus?: a case control study [PDF]

, 2014
Objectives: Diabetes Mellitus is emerging as a major health problem over these years. Present method of blood glucose monitoring by venepuncture is invasive leading to reduced patient compliance and thereby ineffective judicious monitoring.
Babu, Subhas G., Balan, Preethi, Castelino, Renita L., Fazil, Areekat K., Rangare, Anusha L., Shetty, Shishir R., Sucheta, Kumari N.   +6 more
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

The Antidiabetic Activity of Curry Leaves “Murraya Koenigii” on the Glucose Levels, Kidneys, and Islets of Langerhans of Rats with Streptozotocin Induced Diabetes [PDF]

, 2017
Background: The aims of this study were to explore the antihyperglycemic effect of curry leaves, Murraya koenigii "MK" aqueous extract, and to examine its possible protective effects on the islets of Langerhans and kidneys of streptozotocin (STZ ...
Al-Ani, I. M. (Imad), Alazzawi, K. S. (Khalid), Santosa, R. I. (Rahajoe), Saxena, A. K. (Anil), Yankuzo, M. H. (Muhammad)   +4 more
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Propolis effectiveness on the reduction of blood glucose level and improvement of body weight in diabetic model's rat

Qanun Medika: Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya
Propolis is an herbal medicinal plant that contains caffeic acid phenethyl ester. This natural polyphenol compound acts as an antioxidant and can reduce blood glucose levels and increase body weight.
Nur Shani Meida, Bambang Purwanto, Brian Wasita, Senyum Indrakila, Soetrisno Soetrisno   +4 more
doaj   +1 more source

High-normal blood glucose levels may be associated with decreased spatial perception in young healthy adults. [PDF]

, 2018
The negative effects of high normal glucose on cognitive function were previously reported in euglycemic individuals of middle age and the elderly population.
A Boehmer, A Kemeny, A Simmons, AB Scholey, Abdulla Faisal Alshaiji, Abdulrahman Ahmed Qareeballa, AC Guyton, C Lopez, C Messier, FW Akin, G Mazibrada, H Nyborg, H Nyborg, J Bagust, J Bagust, J Bagust, J Bagust, J Cohen, J Waterhouse, JE Sprague, Jeff Bagust, JS Durmer, K Murray, K Noriaki, L Kerti, LC Perlmuter, M Reivich, ME Mortby, MMK Hijazi, Mohamed Wael Mohamed, N Cherbuin, PK Crane, R Abdul Razzak, R Nakashima, R Roky, R Roky, RAA Vingerhoets, Rima Abdul Razzak, RJ McCrimmon, RT Donohoe, S Docherty, S Fitzgerald, S Fitzgerald, Sharon Docherty, Stephen L. Atkin, T Reilly, T Romeas   +46 more
core   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

HUBUNGAN POLA KONSUMSI VITAMIN C TERHADAP KADAR GLUKOSA DARAH DAN TRIGLISERIDA PADA PASIEN DIABETES MELITUS RAWAT JALAN DI RSUD Dr. MOEWARDI [PDF]

, 2015
Background: uncontrolled diabetes mellitus will to complication of various Complications like stroke, hypertension, and heart disease. Complications due to increased production of free radical for high blood glucose levels.
, Elida Soviana, S.Gz., M.Gizi, , Fitriana Mustikaningrum, S.Gz, M.Sc, Nurlita, Nurul   +2 more
core  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Adropin reduces blood glucose levels in mice by limiting hepatic glucose production

Physiological Reports, 2019
Adropin is a liver‐ and brain‐secreted peptide hormone with striking effects on fuel metabolism regulation in a number of tissues. Previous studies demonstrated that adropin secretion is decreased in obese mice subjected to a long‐term high‐fat diet (HFD)
Dharendra Thapa, Bingxian Xie, Janet R. Manning, Manling Zhang, Michael W. Stoner, Brydie R. Huckestein, Lia R. Edmunds, Xueyang Zhang, Nikolaos L. Dedousis, Robert M. O'Doherty, Michael J. Jurczak, Iain Scott   +11 more
doaj   +1 more source