Results 111 to 120 of about 23,604,700 (351)

Kell and Kx blood group systems

Immunohematology, 2015
The Kell and Kx blood group systems are expressed as covalently linked molecules on red blood cells (RBCs). The Kell blood group system is very polymorphic, with 35 antigens assigned to the system.
Gregory A. Denomme
semanticscholar   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Tracheal suctioning improves gas exchange but not hemodynamics in asphyxiated lambs with meconium aspiration. [PDF]

, 2015
BackgroundCurrent neonatal resuscitation guidelines recommend tracheal suctioning of nonvigorous neonates born through meconium-stained amniotic fluid.MethodsWe evaluated the effect of tracheal suctioning at birth in 29 lambs with asphyxia induced by ...
Gugino, Sylvia F, Koenigsknecht, Carmon, Lakshminrusimha, Satyan, Mathew, Bobby, Nair, Jayasree, Nielsen, Lori, Rawat, Munmun, Swartz, Daniel D   +7 more
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Short-term pretreatment with a dual 5α-reductase inhibitor before bipolar transurethral resection of the prostate (b-turp): evaluation of prostate vascularity and decreased surgical blood loss in large prostates [PDF]

, 2015
Objective: To investigate if short-term treatment with dutasteride (8 weeks) before bipolar transurethral resection of the prostate (B-TURP) can reduce intraoperative bleeding, as dutasteride a dual 5α-reductase inhibitor (5-ARI) blocks the conversion of
Amory, Berry, Boccon-Gibod, Boyle, Carlin, De Berardinis, Delakas, Frye, Hahn, Issa, Kravchick, Ku, Lekas, Madersbacher, Marberger, Marks, Martov, Naslund, Oelke, Pareek, Pareek, Pastore, Puchner, Rittmaster, Roehrborn, Roehrborn, Roehrborn, Toi, Zaitsu   +28 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Common hub genes in Uremia and Kidney Renal Clear Cell Carcinoma (KIRC): their role in KIRC pathogenesis through activation of the citrate cycle pathway

BMC Nephrology
Introduction Uremia and Kidney Renal Clear Cell Carcinoma (KIRC) are two significant health conditions that place a considerable burden on patients globally.
Liang Zhao, Huimei Su, Wenjuan Guo, Junfeng Lei   +3 more
doaj   +1 more source

Consensus on Complement Inhibitor Therapy and Management of Paroxysmal Nocturnal Hemoglobinuria

罕见病研究
Paroxysmal nocturnal hemoglobinuria (PNH), a rare clonal disease of hematopoietic stem cells caused by mutations in the phosphatidylinositol N-acetylglucosaminyltransferase subunit A (PIGA) gene, may lead to the deficiency of glycosylated ...
Red Blood Cell Disease (Anemia) Group, Chinese Society of Hematology, Chinese Medical Association
doaj   +1 more source

Effect of obesity on autonomic nervous system [PDF]

, 2011
The present study was carried out on 100 volunteers of which 50 subjects with BMI > 30kg/m2 were included in study group and 50 subjects with BMI < 30kg/m2 (non obese) were included in control group.
Simran Grewal, Vidushi Gupta, Int J Cur Bio Med Sci.
core  

Follow-up of blood-pressure lowering and glucose control in type 2 diabetes. [PDF]

, 2014
BACKGROUND In the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) factorial trial, the combination of perindopril and indapamide reduced mortality among patients with type 2 diabetes, but ...
Arima, H, Billot, L, Chalmers, J, Colagiuri, S, Cooper, M, Davoren, Peter, Glasziou, P, Grobbee, D, Group, ADVANCE-ON Collaboration, Harnett, P, Harrap, S, Heller, S, Hirakawa, Y, Joshi, R, Li, Q, Lisheng, L, MacMahon, S, Mancia, G, Marre, M, Matthews, D, Mogensen, C, Monaghan, H, Neal, B, Patel, A, Perkovic, V, Poulter, N, Rodgers, A, Williams, B, Woodward, M, Zoungas, S   +29 more
core   +4 more sources