Results 71 to 80 of about 23,604,700 (351)

Generation of three human erythroblast-derived iPSC lines (UBTi002-A, UBTi002-B, and UBTi002-C)

Stem Cell Research
We reprogrammed human hematopoietic stem/progenitor cell (HSPC)-derived erythroblasts obtained from a healthy male donor. CD34+ HSPCs were differentiated ex-vivo into erythroid precursor cells and were then nucleofected with four episomal plasmids ...
Martina Auer, Hannah Sophie Klampfl, Peter Schlenke, Isabel Dorn   +3 more
doaj   +1 more source

Structure and function of the blood–brain barrier

Neurobiology of Disease, 2010
Neural signalling within the central nervous system (CNS) requires a highly controlled microenvironment. Cells at three key interfaces form barriers between the blood and the CNS: the blood–brain barrier (BBB), blood–CSF barrier and the arachnoid barrier.
N. Joan Abbott, Adjanie A.K. Patabendige, Diana E.M. Dolman, Siti R. Yusof, David J. Begley   +4 more
doaj   +1 more source

The Analysis of Indices of Cerebral Blood Circulation in Women-smokers [PDF]

, 2017
The results of rheoencephalography of female smokers 17–21 years old and control group were studied and analyzed. The aim of this work was to explain and analyze physiological features of smoking effect on functional changes of regional hemodynamics in ...
Aponchuk, L. (Lyudmila), Shevchuk, T. (Tatiana)   +1 more
core   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Effect of Plectranthus Amboinicus Extract on BUN and Creatinine Levels and Cellular Response Proinflammatory Factors TNF-α and IL-1β on Gout Arthritis Patients [PDF]

, 2014
The purpose of this research was to develop anti-cytokine-based treatment using extract of Plectranthus amboinicus applied to gout arthritis (GA) patients. The research was quasi experimental, with a pretest-posttest randomized control group design.
Martini, S. (Santi), Muniroh, L. (Lailatul), Nindya, T. S. (Triska), Solfaine, R. (Rondius)   +3 more
core   +2 more sources

Erythrogene: a database for in-depth analysis of the extensive variation in 36 blood group systems in the 1000 Genomes Project.

Blood Advances, 2016
Blood group genotyping has recently developed into a clinical tool to improve compatibility of blood transfusions and management of pregnancies. Next-generation sequencing (NGS) is rapidly moving toward routine practice for patient and donor typing and ...
Mattias Möller, Magnus Jöud, J. Storry, M. Olsson   +3 more
semanticscholar   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

The place of D-dimer and L-lactate levels in the early diagnosis of acute mesenteric ischemia [PDF]

, 2015
INTRODUCTION: Acute mesenteric ischemia (AMI) is an abdominal-vascular emergency which is rare and has high mortality rates (60-80 %) due to late diagnosis (1-3).
Aydin, B., Aydin, C., Demirkan, Neşe Çallı, Kaptanoğlu, Bünyamin, Serinken, M., Özban, Murat   +5 more
core   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

A preliminary survey on the use of ART among blood donors in Shenzhen China and its implications to blood safety

BMC Infectious Diseases
Importance The recent introduction of the AIDS pre-exposure or post-exposure prophylaxis (PrEP/PEP) medication has sparked fear of the possible increase of human immunodeficiency virus (HIV) and Treponema pallidum (TP) transfusion-transmission risk due ...
Lilin Wang, He Xie, Fang Zhao, Lukun Zhang, Zhengrong Yang, Yizhong Liu, Tong Li, Tingting Chen, Xiaoxuan Xu, Yingnan Dang, Qi Zhang, Zhicheng Wang, Guochao Wei, Jujun Sun, Jun Xi, Chenze Xi, Jinfeng Zeng, Rong Xia, Limin Chen   +18 more
doaj   +1 more source