Results 1 to 10 of about 746,128 (172)
Identification of Blood-Group Antigens [PDF]
Nature, 1960 The Anti-Globulin (Coombs) Test in Laboratory Practice By Dr. I. Dunsford and Jean Grant. Pp. xiii + 120. (Edinburgh and London: Oliver and Boyd, Ltd., 1959.) 12s 6d net.
Rebecca A. Drummond
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Association of Blood Group Antigen CD59 with Disease [PDF]
Transfusion Medicine and Hemotherapy, 2022 In 2014, the membrane-bound protein CD59 became a blood group antigen. CD59 has been known for decades as an inhibitor of the complement system, located on erythrocytes and on many other cell types. In paroxysmal nocturnal haemoglobinuria (PNH), a stem cell clone with acquired deficiency to express GPI-anchored molecules, including the complement ...
Weinstock C.
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Pemphigus Antigen and Blood Group Substances A and B
Journal of Investigative Dermatology, 1967 Immunofluorescent studies have revealed the presence of antiepithelial immunoglobulins (antibodies) in the sera of patients with the bullous skin disease pemphigus (1, 2). These antibodies attach in vitro and in vivo to a component in stratified epithelia which either belongs to the epithelial cell wall or to the intercellular substance.
Peter J. Grob, Theodor M. Inderbitzin
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Mathematical Modeling Insights into Improving CAR T cell Therapy for Solid Tumors: Antigen Heterogeneity and Bystander Effects [PDF]
npj Systems Biology and Applications, 10(1), 105 (2024), 2023 As an adoptive cellular therapy, Chimeric Antigen Receptor T-cell (CAR T-cell) therapy has shown remarkable success in hematological malignancies, but only limited efficacy against solid tumors. Compared with blood cancers, solid tumors present a unique set of challenges that ultimately neutralize the function of CAR T-cells.
arxiv +1 more source
Does blood type affect the COVID-19 infection pattern? [PDF]
PLoS ONE (2021);16(5): e0251535, 2020 Among the many aspects that characterize the COVID-19 pandemic, two seem particularly challenging to understand: (i) the great geographical differences in the degree of virus contagiousness and lethality which were found in the different phases of the epidemic progression, and (ii) the potential role of the infected people's blood type in both the ...
arxiv +1 more source
A New Blood-Group Antigen [PDF]
Nature, 1951 A SERUM that identifies a new blood-group antigen was obtained from the parturient mother of a baby with erythroblastosis fœtalis. Mrs. Kidd had had five previous pregnancies but no blood transfusions. No previous babies had erythroblastosis fœtalis. She was delivered on April 17, 1950, of a male infant who developed typical erythroblastosis fœtalis ...
Louis K. Diamond +2 more
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Histo-blood group glycans in the context of personalized medicine [PDF]
Biochimica et Biophysica Acta 1860 (2016) 1596-1607, 2019 Background: A subset of histo-blood group antigens including ABO and Lewis are oligosaccharide structures which may be conjugated to lipids or proteins. They are known to be important recognition motifs not only in the context of blood transfusions, but also in infection and cancer development.
arxiv +1 more source
Blood group reckoning: Unraveling the mystery of blood group antigens [PDF]
Annals of Medical Physiology, 2018 No ...
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A dynamical modeling to study the adaptive immune system and the influence of antibodies in the immune memory [PDF]
CMES, vol 45(1) pp 83-96 (2009), 2017 Immunological systems have been an abundant inspiration to contemporary computer scientists. Problem solving strategies, stemming from known immune system phenomena, have been successfully applied to challenging problems of modern computing (MONROY, SAAB, GODINEZ, 2004). Simulation systems and mathematical modeling are also beginning use to answer more
arxiv +1 more source
Blood ties: ABO is a trans-species polymorphism in primates [PDF]
, 2012 The ABO histo-blood group, the critical determinant of transfusion incompatibility, was the first genetic polymorphism discovered in humans. Remarkably, ABO antigens are also polymorphic in many other primates, with the same two amino acid changes responsible for A and B specificity in all species sequenced to date.
arxiv +1 more source