Results 201 to 210 of about 863,756 (239)

Microneedles at the Forefront of Next Generation Theranostics

Advanced Science, EarlyView.
The TOC figure illustrates the revolutionary role of microneedles in modern medicine, showcasing their dual diagnostic and therapeutic functions. On the left, microneedles access interstitial fluid for real‐time monitoring of biomarkers like glucose and hormones.
Chan Wang, Yuan Yang, Jiaqi Zhang, Hanrui Zhang, Qian Wang, Shengmei Ma, Pengfei Zhao, Zhou Li, Yuxin Liu   +8 more
wiley   +1 more source

A Bead‐Based Quantum Dot Immunoassay Integrated with Multi‐Module Microfluidics Enables Real‐Time Multiplexed Detection of Blood Insulin and Glucagon

Advanced Science, EarlyView.
The quantum dot integrated real‐time ELISA or QIRT‐ELISA system integrates a bead‐based quantum dot‐mediated immunoassay (BQI) with a modular microfluidic system to continuously monitor insulin and glucagon in whole blood samples and in a multiplexed setting.
Hesam Abouali, Sanjana Srikant, Md Fahim Al Fattah, Nicole G. Barra, Darryl Chan, Dayan Ban, Jonathan D. Schertzer, Mahla Poudineh   +7 more
wiley   +1 more source

High Fat Low Carbohydrate Diet Is Linked to CNS Autoimmunity Protection

Advanced Science, EarlyView.
Mapping global epidemiological data to macronutrient supply reveals high carbohydrate, in contrast to high fat supply, associates with increased multiple sclerosis (MS) prevalence and incidence. This is confirmed in a mouse MS model, experimental autoimmune encephalomyelitis (EAE), using isocaloric diets: a high carbohydrate diet aggravates, a high ...
Duan Ni, Jian Tan, Julen Reyes, Alistair M Senior, Caitlin Andrews, Jemma Taitz, Camille Potier‐Villette, Claire Wishart, Alanna Spiteri, Laura Piccio, Nicholas Jonathan Cole King, Romain Barrès, David Raubenheimer, Stephen James Simpson, Ralph Nanan, Laurence Macia   +15 more
wiley   +1 more source

KDM6A Deficiency Induces Myeloid Bias and Promotes CMML‐Like Disease Through JAK/STAT3 Activation by Repressing SOCS3

Advanced Science, EarlyView.
Lysine demethylase 6A (KDM6A), an epigenetic regulator expressed in hematopoietic stem and progenitor cells (HSPCs), plays a critical role in hematopoietic homeostasis. Deficiency of KDM6A induces myeloid lineage skewing and drives the development of a chronic myelomonocytic leukemia (CMML)‐like disease.
Huiqiao Chen, Shufen Wang, Ruoyu Dong, Pinghui Yu, Tianyu Li, Liangning Hu, Mowang Wang, Zijun Qian, Hongyu Zhou, Xiaoyan Yue, Limengmeng Wang, Haowen Xiao   +11 more
wiley   +1 more source

LincNEAT1 Encoded‐NEAT1‐31 Promotes Phagocytosis by Directly Activating the Aurora‐A–PI3K–AKT Pathway

Advanced Science, EarlyView.
LincNEAT1 Encoded‐NEAT1‐31 micropeptide directly binds with Aurora‐A and enhanced AKT pathways to pormotes phagocytosis against multi cancer cells. Abstract Macrophages play vital roles in innate and adaptive immunity, and their essential functions are mediated by phagocytosis and antigen presentation.
Jie Li, Jing Zhang, Xixi Li, Xin Liu, Bo Zeng, Jiayue Luo, Huijin Wang, Hanbing Zhang, Xinya Gao   +8 more
wiley   +1 more source

Blood Group Antigens: Blood Group Carbohydrate Antigens [PDF]

, 2009
The most popular blood group antigen system, ABO antigens had been known to consist of alpha1,2-fucosylated galactose substituted with alpha1,3-N-acetylgalactosamine (A) or galactose (B). These biochemical results were clearly confirmed and further investigated by the molecular cloning of blood group A synthase cDNA (Yamamoto et al. 1990a, 1990b).
Koichi Iwamura, Koichi Furukawa, Keiko Furukawa   +2 more
openaire   +1 more source

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The Rare Blood Group Antigen, Wu

Vox Sanguinis, 1976
Abstract. The inheritance of the Wu antigen in three families is described. The observations suggest that the antigen is inherited as a Mendelian dominant character. Wu segregates independently of sex and of the ABO, MNSs, Rh, Lutheran, Duffy and Kidd blood group systems. Independence of Kell is also quite likely. Wu is a very rare antigen.
P. Howell, A. M. Heier Larsen, L. D. Wadsworth, Jens Kjær Jørgensen, L. Kornstad   +4 more
openaire   +3 more sources

A New Blood Group Antigen, Hov

Vox Sanguinis, 1973
Abstract. A new blood group antigen, Hov, is described. The antigen is not closely linked to the MNSs, P, Rhesus secretor, Duffy and Kidd loci, and it is not X‐linked. 1,155 blood samples were tested; two of these had the new antigen.
Agnes Szaloky, Net Kaars Sijpesteijn, Mia van der Hart   +2 more
openaire   +3 more sources

Nomenclature of Blood Group Antigens [PDF]

, 1995
“The term antigen is used in two senses, the first to describe a molecule which generates an immune response and the second a molecule which reacts with anti- bodies or primed T-cells irrespective of its ability to generate them” (Roitt, 1991).
Philippe Rouger, Pierre-Yves Le Pennec
openaire   +1 more source

ABO blood groups and Australia antigen

Clinical Genetics, 1974
The distribution of ABO blood in two groups of people with Australia antigen was studied (121 blood donors and 128 patients) and in 3,091 controls was investigated. There was a significant excess of A in comparison with o when the two groups were combined, and when the two groups were tested for (A + B): (AB +O) individually and together, both were ...
R. Ananthakrishnan, H. Walter, A. Arndt-Hanser   +2 more
openaire   +3 more sources