Results 21 to 30 of about 863,756 (239)

Immunomodulation by imiquimod in patients with high-risk primary melanoma. [PDF]

, 2012
Imiquimod is a synthetic Toll-like receptor 7 (TLR7) agonist approved for the topical treatment of actinic keratoses, superficial basal cell carcinoma, and genital warts.
Antoni Ribas, Barnetson, Begonya Comin-Anduix, Buettiker, Christine Dauphine, Comin-Anduix, Comin-Anduix, Cotter, Craft, DeGiorgi, Diana K. Lee, Erickson, Gaspari, Gibson, Green, Hemmi, Hernan I. Vargas, Hong Nguyen, Ito, Jacquelyn Haskell, James S. Economou, Jason J. Bentow, Kevin W. Bruhn, Lauren Moy, Lee, Ma, Molenkamp, Naylor, Noah Craft, Oh, Ooi, Pei-Lin Chang, Pinzon-Charry, Powell, Prins, Rajpar, Rupa Narayan, Schott, Shanli Tsui, Shu, Stanley, Stephanie Greger, Takeda, Tamiko Konishi, Torres, Urosevic, Veena Vanchinathan, Vuylsteke, Yang   +48 more
core   +2 more sources

Etiology of Severe Non-malaria Febrile Illness in Northern Tanzania: A Prospective Cohort Study. [PDF]

, 2013
The syndrome of fever is a commonly presenting complaint among persons seeking healthcare in low-resource areas, yet the public health community has not approached fever in a comprehensive manner.
AJ Bouley, Anne B. Morrissey, B Nadjm, B Nadjm, B Pastorino, BM Greenwood, CA Petti, Charles Muiruri, CIR Chandler, CJ Murray, CJ Murray, DC Clifton, DR Feikin, EA Reddy, Eng Eong Ooi, Grace D. Kinabo, H Reyburn, HM Biggs, JA Berkley, JA Crump, JA Crump, JA Crump, JA Crump, John A. Bartlett, John A. Crump, JT Hertz, K Baltzell, LE Scott, LK Archibald, M Amexo, M Prabhu, Mathieu Picardeau, MD Bajani, MK Mayhood, MM Levine, N Scaramozzino, OS Levine, PA Connolly, PL Petit, R Lozano, Renee L. Galloway, Robert F. Massung, Robyn A. Stoddard, SI Hay, SJ Olsen, SL Brown, SM Graham, SM Lofgren, TJ O'Dempsey, Venance P. Maro, Wilbrod Saganda, William L. Nicholson, YL Lai   +52 more
core   +6 more sources

The serlogical specificity of the lectin from Lens culinaris [PDF]

, 1973
Lens culinaris, the common lentil, contains a lectin which has been shown to be specific for a glycoprotein saliva antigen and a glycolipoprotein serum antigen.
Heritage, Deborah Ward
core   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Blood group typing in five Afghan populations in the North Hindu-Kush region: implications for blood transfusion practice.

, 2013
International audienceBACKGROUND AND OBJECTIVES: Blood incompatibility arises from individual and ethnic differences in red blood cell (RBC) antigen profiles. This underlines the importance of documenting RBC antigen variability in various ethnic groups.
Chiaroni, J., Di Cristofaro, J., Gallian, P., Mazières, S., Temory, S. A., Vasseur, H.   +5 more
core   +3 more sources

The potential role of T-cells and their interaction with antigen-presenting cells in mediating immunosuppression following trauma-hemorrhage [PDF]

, 2009
Objective: Trauma-hemorrhage results in depressed immune responses of antigen-presenting cells (APCs) and T-cells. Recent studies suggest a key role of depressed T-cell derived interferon (IFN)-g in this complex immune cell interaction.
Abraham E., Angele MK, Angele MK, Christian P. Schneider, Christian R. Walz, Christiane J. Bruns, de Saint-Vis B., Ertel W., Eugen Faist, Florian Loehe, Irshad H. Chaudry, Landy M., Markus Albertsmeier, Martin K. Angele, Ransom J., Siegfried Zedler   +15 more
core   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Blood types [PDF]

, 2011
Krv je specifična tjelesna tekućina koja se sastoji od krvnih stanica i krvne plazme. Krvna grupa je klasificirana na temelju prisutnosti ili odsutnosti naslijeđenih antigena koji se nalaze na površini crvenih krvnih stanica.
Brižić, Matea
core   +2 more sources

Cloning and expression of porcine β1,4 N-acetylgalactosaminyl transferase encoding a new xenoreactive antigen [PDF]

, 2014
Xenograft rejection of pigs organs with an engineered mutation in the GGTA-1 gene (GTKO) remains a predominantly antibody mediated process which is directed to a variety of non-Gal protein and carbohydrate antigens.
Byrne, GW, Du, Z, Kogelberg, H, McGregor, CG, Stalboerger, P   +4 more
core   +2 more sources

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source