Results 41 to 50 of about 748,429 (317)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Determination of ABO blood group based on secretors or non-secretors analysis in body fluids
Qanun Medika: Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah SurabayaCriminal acts often leave traces analyzed by law enforcement, especially by the Indonesian National Police (POLRI). Sometimes, various items were found and analyzed to link the victim and the perpetrator.
Fery Setiawan +4 more
doaj +1 more source
FEBS Letters, EarlyView.Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung +6 more
wiley +1 more source
Quantile regression for mixed models with an application to examine blood pressure trends in China [PDF]
Annals of Applied Statistics 2015, Vol. 9, No. 3, 1226-1246, 2015 Cardiometabolic diseases have substantially increased in China in the past 20 years and blood pressure is a primary modifiable risk factor. Using data from the China Health and Nutrition Survey, we examine blood pressure trends in China from 1991 to 2009, with a concentration on age cohorts and urbanicity.
arxiv +1 more source
Passive modulation of blood-group antigens. [PDF]
Proceedings of the National Academy of Sciences, 1979 Rh-positive erythrocytes were enriched and depleted of membrane cholesterol, and the mediated change in the degree of exposure of the D antigens was determined by fluorescence-activated cell sorting, using indirect fluorescent antibody labeling.
Miry Souroujon, Meir Shinitzky
openaire +3 more sources
Blood Group Characteristics in Colorectal Cancers
Turkish Journal of Colorectal Disease, 2018 Aim: Colorectal cancer (CRC) is the third most common cancer in the world. Tumors are most commonly located in the rectosigmoid region. There are many factors in the etiology such as age, geographical features, family history, obesity, diet, and history ...
Şahin Kahramanca +3 more
doaj +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
The Alteration of Blood Group Antigens by Carbodiimide
Experimental Biology and Medicine, 1972 SummaryEthyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (CDD) inhibits the expression of many blood group antigens of the human red cell. A notable exception is the ABO system. The alteration did not seem to be reversible by ordinary methods.
Kay J. Nielsen +3 more
openaire +3 more sources
Molecules, 2020 Lectins mediate adhesion of pathogens to host tissues, filling in a key role in the first steps of infection. Belonging to the opportunistic pathogen Burkholderia cenocepacia, BC2L-C is a superlectin with dual carbohydrate specificity, believed to ...
Rafael Bermeo +2 more
doaj +1 more source