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Biologic functions of blood group antigens

Current Opinion in Hematology, 1996
In the past few years, we have learned a great deal about the biologic function of structures bearing blood group antigens. Some blood group antigen-bearing proteins function as major transport channels within the erythrocyte membrane; these include the anion transporter (band 3: Diego and Wright antigens), the water channel (aquaporin: Colton antigens)
Marilyn J. Telen, Raja Mudad
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Blood Group Antigen Xga in Gibbons

Nature, 1964
THE antigen Xga, which in man is an X-linked dominant character1, was looked for in various mammals but was found only in gibbons. It was not found in the following animals: 67 chimpanzees (Pan satyrus), 2 gorillas (Gorilla gorilla gorilla), 20 orangutans (Pongo pygmaeus), 60 baboons (Papio cynocephalus), 31 Celebes black apes (Cynopithecus niger), 4 ...
June Gavin   +4 more
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Blood group antigens in health and disease

Current Opinion in Hematology, 2005
Blood group antigens are polymorphic, inherited structures located on the surface of the red blood cell. They have long played an important role in identifying matched blood products for transfusion. Recent studies have identified varied and important functions for some of these molecules in cell physiology and human pathology.Many novel functions ...
Narla Mohandas, Anupama Narla
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A New Blood Group Antigen, ‘Jobbins’

Nature, 1947
A multiparous woman with seven previous normal pregnancies was first tested serologically eight months after the commencement of the eighth pregnancy. She was typed as group Arr. The first serum sample showed a weak anti-Rh agglutinin (type anti-D) with a titre of 2, associated with an ‘incomplete’ antibody which was first thought to be ‘incomplete ...
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The Blood Group Antigen Ula (Karhula)

Vox Sanguinis, 1968
SummaryThe serum of a Finnish patient contains an antibody to a previously unknown red cell antigen provisionally called Ula. The antigen is possessed by 2.6% of 2620 Helsinki blood donors though in certain Finnish isolates it is more frequent: it is inherited as a dominant character.
Ruth Sanger   +6 more
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Immunodiffusion Studies of Blood Group A Antigen1

Vox Sanguinis, 1974
Abstract. Stromata of blood group A1 erythrocytes fragmented by ultrasound were studied by means of double diffusion in gel. In many instances the reactions with immune anti‐A sera were composed of two lines. Evidence was presented that group A1 secretor saliva contains all the A antigenic specificities present on the stromata.
James F. Mohn, Ulana Loza, Felix Milgrom
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Blood group antigens reveal their maker

Blood, 2008
For the first time, heterozygous mutations within human EKLF/KLF1 have been identified and shown to alter the expression of blood group antigens. Subtle variations in certain groups of genes may not lead to a dramatic clinical presentation, but when enriched within human subpopulations, they ...
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Studies on the Blood Group Antigen Ina

Immunological Communications, 1980
Anti-Ina antibodies have been observed in 30 of the 41 anti-Rh donors hyperimmunised with group O Ror In(a+) blood. They have also been found in four of 60 Rh immunised women. In three of these the husbands and previous children were In(a+). However, there was no evidence of haemolytic disease of the newborn due to anti-Ina antibodies alone.
B. B. Parab   +3 more
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What is a blood group antigen? [PDF]

open access: possibleTransfusion, 1992
Geoff Daniels   +2 more
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ABO Blood-group Antigens in Oral Cancer

Journal of Dental Research, 2005
Tumor progression is often associated with altered glycosylation of the cell-surface proteins and lipids. The peripheral part of these cell-surface glycoconjugates often carries carbohydrate structures related to the ABO and Lewis blood-group antigens.
Dabelsteen, E., Gao, S.
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