ATF5‐Dependent GDF15 Expression Mediates Anesthesia‐Induced Neuroprotection Against Stroke
Anesthesia‐induced preconditioning protects against perioperative stroke. By manipulating ATF5 in excitatory neurons, it is shown that anesthesia‐driven ATF5 upregulation activates the mitochondrial unfolded protein response (UPRmt) and elevates GDF15 expression.
Xianshu Ju +11 more
wiley +1 more source
Cord Blood Bilirubin, Albumin, and Hemoglobin as Predictors of Significant Hyperbilirubinemia in ABO-Incompatible Newborns: A Prospective Study in a Tertiary Neonatal Center in India. [PDF]
George J +3 more
europepmc +1 more source
THE INCIDENCE, CAUSE, AND SIGNIFICANCE OF IMMEDIATE AND DELAYED OLIGURIA OR ANURIA AFTER HUMAN RENAL TRANSPLANTATION. [PDF]
HOLMES, JH +3 more
core
A series of vancomycin‐antimicrobial peptide conjugates is synthesized and evaluated to identify the optimal combination. Vm‐MSI, selected from multiple candidates, exhibited potent activity against vancomycin‐resistant and Gram‐negative bacteria by disrupting membranes and inducing oxidative stress, thereby expanding vancomycin's antibacterial ...
Shuangyu Li +7 more
wiley +1 more source
Construction and Evaluation of a Prediction Model for Neonatal Hyperbilirubinemia. [PDF]
Xu S, Guo X, Li C, Chen J, Zhang C.
europepmc +1 more source
Dysregulated Tissue resident macrophage (TRMs) link to autoimmune inflammation. SMURF2 mediates Lys‐27 (K27)‐linked ubiquitination of p‐TBK1 and its degradation, which inhibits CSF1R signaling‐triggered TRM proliferation, thereby restraining the autoimmune inflammation.
Xiang An +8 more
wiley +1 more source
Sero-typing of human lymphocyte antigens: Preliminary trials on long-term kidney homograft survivors [PDF]
Marchioro, TL, Starzl, TE, Terasaki, PI
core
CircSMEK1 Suppresses HCC via the hnRNPK‐IGF2‐AKT Axis: A Diagnostic Biomarker and Therapeutic Target
CircSMEK1 is downregulated in MASH/HCC and predicts poor prognosis. It suppresses tumor progression by promoting hnRNPK ubiquitination and inhibiting the IGF2/PI3K/AKT axis, while its loss activates immunosuppressive cancer‐associated fibroblasts. Serum circSMEK1 serves as a non‐invasive diagnostic biomarker, and its restoration potently inhibits HCC ...
Peilan Guo +15 more
wiley +1 more source
Risk factors for bronchiolitis obliterans syndrome after hematopoietic stem cell transplantation: a systematic review and meta-analysis. [PDF]
Pu G +8 more
europepmc +1 more source

