Results 241 to 250 of about 66,618 (347)

Engineering Decavalent, Sperm‐Binding Laminin‐IgG Hybrid Antibodies for Potent Non‐Hormonal Contraception

Advanced Science, EarlyView.
This study investigates a highly multivalent mAb platform fusing Laminin‐511 heterotrimerization domains with Fabs and IgG1‐Fc as a non‐hormonal contraceptive. The most potent molecule ‘LamH10’, possessing 10 Fabs, rapidly achieved >99% reduction in progressively motile sperm at just 33µg per dose in sheep, making the laminin‐IgG hybrid platform the ...
Alison Schaefer, Keiichiro Kushiro, Bhawana Shrestha, Yong Zhu, Alysha Panjwani, Lauren Dawson, Haley Flowers, Kathleen L. Vincent, Samuel K. Lai   +8 more
wiley   +1 more source

Correlations between blood group and Rh factor in families and autism spectrum disorder: A comprehensive analysis. [PDF]

Sci Rep
Al-Salihy AAS.
europepmc   +1 more source

Principles of whole organ transplantation [PDF]

, 1984
Iwatsuki, S, Shaw, BW, Starzl, TE
core  

m6A Reader hnRNPA2B1 Modulates Late Pachytene Progression in Male Meiosis Through Post‐Transcriptional Control

Advanced Science, EarlyView.
As an m6A reader, hnRNPA2B1 predominantly regulates specific transcripts (e.g., Ep400, Rrs1) that are essential for chromosome organization and remodeling in an m6A‐dependent manner. Furthermore, it is demonstrated to interact with factors involved in mRNA processing and translation. This dual functionality is pivotal for ensuring the proper occurrence
Lisha Yin, Yuting Zhang, Bingqian Zhang, Jin Zhang, Mengneng Xiong, Nan Jiang, Jinxin Xiao, Huihui Gao, Wenjing Xiong, Xiaoli Wang, Fengli Wang, Shuiqiao Yuan   +11 more
wiley   +1 more source

How to select the correct patients for home phototherapy of neonatal hyperbilirubinaemia-a retrospective population-based implementation study. [PDF]

Eur J Pediatr
Pettersson M, Lai C, Ohlin A.
europepmc   +1 more source

Anti-gal A/B, a novel anti-blood group antibody identified in recipients of abo-incompatible kidney allografts1

, 2002
Uri Galili, Hideki Ishida, Kazunari Tanabe, Hiroshi Toma   +3 more
openalex   +1 more source

Macrophage Zc3h12c Limits Tissue Inflammation and Injury via Alternative Splicing of Pre‐mRNA

Advanced Science, EarlyView.
This work defines the context‐dependent function of Zc3h12c in macrophages using the Tnfrsf11a‐Cre system. It reveals Zc3h12c's dual mechanism—regulating RNA degradation and alternative splicing—with STAT1 as a key target. The findings elucidate a novel post‐transcriptional pathway and identify STAT1 isoforms as potential therapeutic targets for kidney
Chenyu Li, Julian Aurelio Marschner, Yoshihiro Kusunoki, Ningxin Zhang, Xiaoxin Li, Hao Deng, Zhibo Zhao, Kanako Watanabe‐Kusunoki, Zhihui Zhu, Yan Xu, Stefanie Steiger, Maciej Lech, Katalin Susztak, Christian Schulz, Hans‐Joachim Anders   +14 more
wiley   +1 more source

Perspective: host factors variants and the underlying causes of long COVID. [PDF]

Front Med (Lausanne)
Pasharawipas T.
europepmc   +1 more source

Viral Systemic Movement Is Enhanced by Alteration of a Structural Phloem Protein by the Insect Vector

Advanced Science, EarlyView.
Aphids release salivary protein GLD into plants, which induces ROS in the phloem. This leads to the intermolecular disulfide bonds formation among SEO proteins, promoting their transition from the dispersed state to the aggregated state. SEO can interact with CMV CP.
Huijuan Guo, Qingyun Shi, Xiaoyu Ling, Yuting Wu, Lin He, Danyang Li, Keyan Zhu‐Salzman, Yucheng Sun   +7 more
wiley   +1 more source

Plasmids of two novel incompatibility groups IncFII_pPROV114-NR and Inc_pCHS4.1-3 from <i>Providencia</i>. [PDF]

Virulence
Lu X, He J, Zheng Y, Chen F, Luo J, Ma K, Yang F, Wang P, Zhou D, Gao B, Yin Z.   +10 more
europepmc   +1 more source